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Effect of dialysis type on serum lipids, apolipoproteins, and lipoproteins.
Ren Fail 2006; 28(7):567-71RF

Abstract

AIM

Dyslipidemia is common among patients with end-stage renal disease, whether treated by hemodialysis (HD) or peritoneal dialysis (PD). However, there are not enough data about the effect of dialysis type on serum lipoprotein (a) [Lp(a)], apolipoprotein (a) [Apo(a)], apolipoprotein (b) [Apo(b)], and lipid levels. The aim of this study was to determine the effect of dialysis type on serum lipid levels.

MATERIALS AND METHODS

This study enrolled 40 HD patients (20 men and 20 women, aged 48.1 +/- 17.6 years) and 69 PD patients (35 men and 34 women, aged 45.2 +/- 16.3 years). Serum lipid profile including total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), triglyceride (TG), Apo(a), Apo(b), and Lp(a) were determined in HD and PD patients. Patients who have used statins within the last six months were not included in the study.

RESULTS

No significant differences in TC, LDL-C, HDL-C, TG, Apo(a), Apo(b), or Lp(a) serum levels were found between HD and PD patients. Serum TC, LDL-C, HDL-C, TG, Apo(a), Apo(b), and Lp(a) in HD and PD patients were 172.2 +/- 42.7 (mg/dL) vs. 181.0 +/- 53.0 (mg/dL), 97.2 +/- 36.2 (mg/dL) vs. 101.4 +/- 33.6 (mg/dL), 45.3 +/- 11.9 (mg/dL) vs. 41.4 +/- 11.1 (mg/dL), 144.7 +/- 71.8 (mg/dL) vs. 173.0 +/- 76.8 (mg/dL), 1.2 +/- 0.5 (g/L) vs. 1.0 +/- 0.2 (g/L), 0.9 +/- 0.3 (g/L) vs. 1.2 +/- 0.3 (g/L), and 43.1 +/- 40.6 (mg/dL) vs. 46.0 +/- 42.7 (mg/dL), respectively.

CONCLUSION

The results of this study show that the maintenance CAPD treatment is associated with more pronounced alterations of the lipoproteins and lipid metabolism than those observed during HD treatment.

Authors+Show Affiliations

Department of Nephrology, Fatih University, Faculty of Medicine, Turkey. drkanbay@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17050239

Citation

Kanbay, Mehmet, et al. "Effect of Dialysis Type On Serum Lipids, Apolipoproteins, and Lipoproteins." Renal Failure, vol. 28, no. 7, 2006, pp. 567-71.
Kanbay M, Delibasi T, Kaya A, et al. Effect of dialysis type on serum lipids, apolipoproteins, and lipoproteins. Ren Fail. 2006;28(7):567-71.
Kanbay, M., Delibasi, T., Kaya, A., Aydogan, T., Koca, C., Akcay, A., ... Yigitoglu, R. (2006). Effect of dialysis type on serum lipids, apolipoproteins, and lipoproteins. Renal Failure, 28(7), pp. 567-71.
Kanbay M, et al. Effect of Dialysis Type On Serum Lipids, Apolipoproteins, and Lipoproteins. Ren Fail. 2006;28(7):567-71. PubMed PMID: 17050239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of dialysis type on serum lipids, apolipoproteins, and lipoproteins. AU - Kanbay,Mehmet, AU - Delibasi,Tuncay, AU - Kaya,Arif, AU - Aydogan,Timucin, AU - Koca,Cemile, AU - Akcay,Ali, AU - Duranay,Murat, AU - Yigitoglu,Ramazan, PY - 2006/10/20/pubmed PY - 2007/2/1/medline PY - 2006/10/20/entrez SP - 567 EP - 71 JF - Renal failure JO - Ren Fail VL - 28 IS - 7 N2 - AIM: Dyslipidemia is common among patients with end-stage renal disease, whether treated by hemodialysis (HD) or peritoneal dialysis (PD). However, there are not enough data about the effect of dialysis type on serum lipoprotein (a) [Lp(a)], apolipoprotein (a) [Apo(a)], apolipoprotein (b) [Apo(b)], and lipid levels. The aim of this study was to determine the effect of dialysis type on serum lipid levels. MATERIALS AND METHODS: This study enrolled 40 HD patients (20 men and 20 women, aged 48.1 +/- 17.6 years) and 69 PD patients (35 men and 34 women, aged 45.2 +/- 16.3 years). Serum lipid profile including total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), triglyceride (TG), Apo(a), Apo(b), and Lp(a) were determined in HD and PD patients. Patients who have used statins within the last six months were not included in the study. RESULTS: No significant differences in TC, LDL-C, HDL-C, TG, Apo(a), Apo(b), or Lp(a) serum levels were found between HD and PD patients. Serum TC, LDL-C, HDL-C, TG, Apo(a), Apo(b), and Lp(a) in HD and PD patients were 172.2 +/- 42.7 (mg/dL) vs. 181.0 +/- 53.0 (mg/dL), 97.2 +/- 36.2 (mg/dL) vs. 101.4 +/- 33.6 (mg/dL), 45.3 +/- 11.9 (mg/dL) vs. 41.4 +/- 11.1 (mg/dL), 144.7 +/- 71.8 (mg/dL) vs. 173.0 +/- 76.8 (mg/dL), 1.2 +/- 0.5 (g/L) vs. 1.0 +/- 0.2 (g/L), 0.9 +/- 0.3 (g/L) vs. 1.2 +/- 0.3 (g/L), and 43.1 +/- 40.6 (mg/dL) vs. 46.0 +/- 42.7 (mg/dL), respectively. CONCLUSION: The results of this study show that the maintenance CAPD treatment is associated with more pronounced alterations of the lipoproteins and lipid metabolism than those observed during HD treatment. SN - 0886-022X UR - https://www.unboundmedicine.com/medline/citation/17050239/Effect_of_dialysis_type_on_serum_lipids_apolipoproteins_and_lipoproteins_ L2 - http://www.tandfonline.com/doi/full/10.1080/08860220600839761 DB - PRIME DP - Unbound Medicine ER -