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Comparison of a bolus of fentanyl with an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation.
J Oral Maxillofac Surg. 2006 Nov; 64(11):1577-82.JO

Abstract

PURPOSE

This study was designed to compare hemodynamic changes, respiratory depression, and patient satisfaction between a bolus of fentanyl and an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation.

PATIENTS AND METHODS

Forty patients were randomly assigned to receive either a bolus of fentanyl (n = 24) or an infusion of alfentanil (n = 16) in combination with target-controlled propofol infusion. Hemodynamic changes, respiratory depression, sedation, and cooperation scores were recorded during surgery and patient satisfaction scores were assessed after surgery.

RESULTS

Changes in mean blood pressure, heart rate, or oxygen saturation within and between the groups were not significant throughout the procedure. There were no significant differences in sedation, cooperation, and patient satisfaction scores between the 2 groups.

CONCLUSION

Because there was no difference in hemodynamic variables and patient satisfaction scores between a bolus of fentanyl and an infusion of alfentanil during target-controlled propofol infusion, both combinations are suitable for conscious sedation in third molar extraction.

Authors+Show Affiliations

Department of Anesthesiology and Pain Medicine, Gachon University of Medicine and Science, Gil Medical Center, Incheon, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17052581

Citation

Kwak, Hyun J., et al. "Comparison of a Bolus of Fentanyl With an Infusion of Alfentanil During Target-controlled Propofol Infusion in Third Molar Extraction Under Conscious Sedation." Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons, vol. 64, no. 11, 2006, pp. 1577-82.
Kwak HJ, Kim JY, Kwak YL, et al. Comparison of a bolus of fentanyl with an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation. J Oral Maxillofac Surg. 2006;64(11):1577-82.
Kwak, H. J., Kim, J. Y., Kwak, Y. L., Park, W. S., & Lee, K. C. (2006). Comparison of a bolus of fentanyl with an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons, 64(11), 1577-82.
Kwak HJ, et al. Comparison of a Bolus of Fentanyl With an Infusion of Alfentanil During Target-controlled Propofol Infusion in Third Molar Extraction Under Conscious Sedation. J Oral Maxillofac Surg. 2006;64(11):1577-82. PubMed PMID: 17052581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of a bolus of fentanyl with an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation. AU - Kwak,Hyun J, AU - Kim,Ji Y, AU - Kwak,Young L, AU - Park,Won S, AU - Lee,Kyung C, PY - 2005/04/28/received PY - 2005/08/03/revised PY - 2005/11/23/accepted PY - 2006/10/21/pubmed PY - 2006/12/9/medline PY - 2006/10/21/entrez SP - 1577 EP - 82 JF - Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons JO - J Oral Maxillofac Surg VL - 64 IS - 11 N2 - PURPOSE: This study was designed to compare hemodynamic changes, respiratory depression, and patient satisfaction between a bolus of fentanyl and an infusion of alfentanil during target-controlled propofol infusion in third molar extraction under conscious sedation. PATIENTS AND METHODS: Forty patients were randomly assigned to receive either a bolus of fentanyl (n = 24) or an infusion of alfentanil (n = 16) in combination with target-controlled propofol infusion. Hemodynamic changes, respiratory depression, sedation, and cooperation scores were recorded during surgery and patient satisfaction scores were assessed after surgery. RESULTS: Changes in mean blood pressure, heart rate, or oxygen saturation within and between the groups were not significant throughout the procedure. There were no significant differences in sedation, cooperation, and patient satisfaction scores between the 2 groups. CONCLUSION: Because there was no difference in hemodynamic variables and patient satisfaction scores between a bolus of fentanyl and an infusion of alfentanil during target-controlled propofol infusion, both combinations are suitable for conscious sedation in third molar extraction. SN - 0278-2391 UR - https://www.unboundmedicine.com/medline/citation/17052581/Comparison_of_a_bolus_of_fentanyl_with_an_infusion_of_alfentanil_during_target_controlled_propofol_infusion_in_third_molar_extraction_under_conscious_sedation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0278-2391(06)01396-6 DB - PRIME DP - Unbound Medicine ER -