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Oral manifestations in HIV/AIDS infected patients from India.
Oral Dis. 2006 Nov; 12(6):537-42.OD

Abstract

OBJECTIVES

To assess types and prevalence of HIV-related oral lesions among HIV-infected individuals in south India and to correlate common oral findings with co-morbidities, gender, age and medication.

SUBJECTS AND METHODS

One hundred and one patients with HIV infection or AIDS at infectious diseases units of Attavar Hospital, Mangalore, and medical wards of Kasturba Medical College, Manipal, were selected. Sociodemographic information was obtained using a structured questionnaire. Oral lesions were diagnosed according to the presumptive criteria of EEC-Clearinghouse Classification. Clinical history was retrieved from patient's medical records.

RESULTS

Erythematous candidiasis (44.5%), melanotic hyperpigmentaion (34.6%) and xerostomia (29.7%) were among the most common oral manifestations. A significant association was found between oral candidiasis and advanced immunosuppression (P < 0.05). Oral hairy leukoplakia (OHL) was predominant in individuals <35 years (P < 0.05). Melanotic hyperpigmentation was significantly associated with highly active antiretroviral therapy (P < 0.05). OHL was more frequent in patients with HIV-associated tuberculosis. Linear gingival erythema was more predominant in females.

CONCLUSIONS

Oral hairy leukoplakia showed a positive relationship with patients younger than 35 years. Oral candidiasis can act as a marker for immunosuppression. Angular cheilitis was predominant in the symptomatic stage.

Authors+Show Affiliations

Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Karnataka, India. drgaurav7479@rediffmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17054765

Citation

Sharma, G, et al. "Oral Manifestations in HIV/AIDS Infected Patients From India." Oral Diseases, vol. 12, no. 6, 2006, pp. 537-42.
Sharma G, Pai KM, Suhas S, et al. Oral manifestations in HIV/AIDS infected patients from India. Oral Dis. 2006;12(6):537-42.
Sharma, G., Pai, K. M., Suhas, S., Ramapuram, J. T., Doshi, D., & Anup, N. (2006). Oral manifestations in HIV/AIDS infected patients from India. Oral Diseases, 12(6), 537-42.
Sharma G, et al. Oral Manifestations in HIV/AIDS Infected Patients From India. Oral Dis. 2006;12(6):537-42. PubMed PMID: 17054765.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral manifestations in HIV/AIDS infected patients from India. AU - Sharma,G, AU - Pai,K M, AU - Suhas,S, AU - Ramapuram,J T, AU - Doshi,D, AU - Anup,N, PY - 2006/10/24/pubmed PY - 2007/1/5/medline PY - 2006/10/24/entrez SP - 537 EP - 42 JF - Oral diseases JO - Oral Dis VL - 12 IS - 6 N2 - OBJECTIVES: To assess types and prevalence of HIV-related oral lesions among HIV-infected individuals in south India and to correlate common oral findings with co-morbidities, gender, age and medication. SUBJECTS AND METHODS: One hundred and one patients with HIV infection or AIDS at infectious diseases units of Attavar Hospital, Mangalore, and medical wards of Kasturba Medical College, Manipal, were selected. Sociodemographic information was obtained using a structured questionnaire. Oral lesions were diagnosed according to the presumptive criteria of EEC-Clearinghouse Classification. Clinical history was retrieved from patient's medical records. RESULTS: Erythematous candidiasis (44.5%), melanotic hyperpigmentaion (34.6%) and xerostomia (29.7%) were among the most common oral manifestations. A significant association was found between oral candidiasis and advanced immunosuppression (P < 0.05). Oral hairy leukoplakia (OHL) was predominant in individuals <35 years (P < 0.05). Melanotic hyperpigmentation was significantly associated with highly active antiretroviral therapy (P < 0.05). OHL was more frequent in patients with HIV-associated tuberculosis. Linear gingival erythema was more predominant in females. CONCLUSIONS: Oral hairy leukoplakia showed a positive relationship with patients younger than 35 years. Oral candidiasis can act as a marker for immunosuppression. Angular cheilitis was predominant in the symptomatic stage. SN - 1354-523X UR - https://www.unboundmedicine.com/medline/citation/17054765/Oral_manifestations_in_HIV/AIDS_infected_patients_from_India_ L2 - https://doi.org/10.1111/j.1601-0825.2006.01232.x DB - PRIME DP - Unbound Medicine ER -