Tags

Type your tag names separated by a space and hit enter

Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection.
Endoscopy 2006; 38(10):996-1000E

Abstract

BACKGROUND AND STUDY AIMS

Endoscopic mucosal resection (EMR) is a widely accepted treatment for early gastric cancer; however, incomplete resection with residual local disease and recurrences continues to be a difficult problem. The aim of this study was to evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for residual/local recurrent early gastric cancer lesions after EMR.

PATIENTS AND METHODS

The en bloc resection rate, histologically complete resection rate, complications, and local recurrence were assessed in 15 patients who underwent ESD for residual/local recurrent early gastric cancer lesions after EMR.

RESULTS

The nonlifting sign after injection of a glycerin solution was positive due to scar formation in all cases. En bloc resection was attempted in all cases, with a complete resection rate of 93.3 % (14 of 15). The lesion was completely resected with histologically adequate margins in the 14 patients who received complete en bloc resection. The average operation time was 85.4 +/- 52.9 min, and the mean follow-up period for all patients was 18.1 +/- 7.4 months. Major bleeding during the procedure in one case was the only complication (one of 15, 6.7 %). None of the patients experienced recurrence of early gastric cancer after ESD.

CONCLUSIONS

ESD appears to be a safe and effective treatment for residual/local recurrent early gastric cancer lesions after EMR, and it is useful for histological confirmation of successful treatment.

Authors+Show Affiliations

Dept. of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17058164

Citation

Oka, S, et al. "Endoscopic Submucosal Dissection for Residual/local Recurrence of Early Gastric Cancer After Endoscopic Mucosal Resection." Endoscopy, vol. 38, no. 10, 2006, pp. 996-1000.
Oka S, Tanaka S, Kaneko I, et al. Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection. Endoscopy. 2006;38(10):996-1000.
Oka, S., Tanaka, S., Kaneko, I., Mouri, R., Hirata, M., Kanao, H., ... Chayama, K. (2006). Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection. Endoscopy, 38(10), pp. 996-1000.
Oka S, et al. Endoscopic Submucosal Dissection for Residual/local Recurrence of Early Gastric Cancer After Endoscopic Mucosal Resection. Endoscopy. 2006;38(10):996-1000. PubMed PMID: 17058164.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection. AU - Oka,S, AU - Tanaka,S, AU - Kaneko,I, AU - Mouri,R, AU - Hirata,M, AU - Kanao,H, AU - Kawamura,T, AU - Yoshida,S, AU - Yoshihara,M, AU - Chayama,K, PY - 2006/10/24/pubmed PY - 2007/1/12/medline PY - 2006/10/24/entrez SP - 996 EP - 1000 JF - Endoscopy JO - Endoscopy VL - 38 IS - 10 N2 - BACKGROUND AND STUDY AIMS: Endoscopic mucosal resection (EMR) is a widely accepted treatment for early gastric cancer; however, incomplete resection with residual local disease and recurrences continues to be a difficult problem. The aim of this study was to evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for residual/local recurrent early gastric cancer lesions after EMR. PATIENTS AND METHODS: The en bloc resection rate, histologically complete resection rate, complications, and local recurrence were assessed in 15 patients who underwent ESD for residual/local recurrent early gastric cancer lesions after EMR. RESULTS: The nonlifting sign after injection of a glycerin solution was positive due to scar formation in all cases. En bloc resection was attempted in all cases, with a complete resection rate of 93.3 % (14 of 15). The lesion was completely resected with histologically adequate margins in the 14 patients who received complete en bloc resection. The average operation time was 85.4 +/- 52.9 min, and the mean follow-up period for all patients was 18.1 +/- 7.4 months. Major bleeding during the procedure in one case was the only complication (one of 15, 6.7 %). None of the patients experienced recurrence of early gastric cancer after ESD. CONCLUSIONS: ESD appears to be a safe and effective treatment for residual/local recurrent early gastric cancer lesions after EMR, and it is useful for histological confirmation of successful treatment. SN - 0013-726X UR - https://www.unboundmedicine.com/medline/citation/17058164/Endoscopic_submucosal_dissection_for_residual/local_recurrence_of_early_gastric_cancer_after_endoscopic_mucosal_resection_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-944780 DB - PRIME DP - Unbound Medicine ER -