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Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions.
Arch Intern Med. 2006 Oct 23; 166(19):2109-16.AI

Abstract

BACKGROUND

Evidence has been emerging that anxiety disorders are associated with several physical health conditions. We used the first community survey, which assessed physical conditions based on physician assessment and included standardized diagnostic assessment of mental disorders by trained health professionals, to examine the relationship between anxiety disorders and physical conditions.

METHODS

The German Health Survey (N = 4181; response rate, 87.6%; ages 18-65 years) used the Composite International Diagnostic Interview to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition mood, substance use, and anxiety disorders (panic disorder, social phobia, specific phobia, generalized anxiety disorder, agoraphobia, obsessive-compulsive disorder) and a standardized medical interview supplemented by laboratory data to assess a broad range of physical conditions. The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) was used to measure health-related quality of life. Number of days of role impairment was used to measure past 30-day disability.

RESULTS

After adjusting for sociodemographic factors and other common mental disorders, the presence of an anxiety disorder was significantly associated with thyroid disease, respiratory disease, gastrointestinal disease, arthritis, migraine headaches, and allergic conditions (adjusted odds ratios between 1.39 and 2.12; P<.05). Compared with physical disorders alone, the presence of comorbid anxiety disorder with 1 or more physical disorders was associated with poorer physical component scores on the SF-36 (adjusted mean scores for physical condition alone and physical condition with anxiety disorder, 48.50 and 45.86, respectively; P<.001) and past 30-day disability due to physical problems (adjusted odds ratio, 1.69; 95% confidence interval, 1.20-2.37).

CONCLUSION

Anxiety disorders are independently associated with several physical conditions in the community, and this comorbidity is significantly associated with poor quality of life and disability.

Authors+Show Affiliations

Department of Psychiatry and Community Health Sciences, University of Manitoba, Winnipeg, Canada. sareen@cc.umanitoba.caNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17060541

Citation

Sareen, Jitender, et al. "Disability and Poor Quality of Life Associated With Comorbid Anxiety Disorders and Physical Conditions." Archives of Internal Medicine, vol. 166, no. 19, 2006, pp. 2109-16.
Sareen J, Jacobi F, Cox BJ, et al. Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions. Arch Intern Med. 2006;166(19):2109-16.
Sareen, J., Jacobi, F., Cox, B. J., Belik, S. L., Clara, I., & Stein, M. B. (2006). Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions. Archives of Internal Medicine, 166(19), 2109-16.
Sareen J, et al. Disability and Poor Quality of Life Associated With Comorbid Anxiety Disorders and Physical Conditions. Arch Intern Med. 2006 Oct 23;166(19):2109-16. PubMed PMID: 17060541.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Disability and poor quality of life associated with comorbid anxiety disorders and physical conditions. AU - Sareen,Jitender, AU - Jacobi,Frank, AU - Cox,Brian J, AU - Belik,Shay-Lee, AU - Clara,Ian, AU - Stein,Murray B, PY - 2006/10/25/pubmed PY - 2006/12/9/medline PY - 2006/10/25/entrez SP - 2109 EP - 16 JF - Archives of internal medicine JO - Arch Intern Med VL - 166 IS - 19 N2 - BACKGROUND: Evidence has been emerging that anxiety disorders are associated with several physical health conditions. We used the first community survey, which assessed physical conditions based on physician assessment and included standardized diagnostic assessment of mental disorders by trained health professionals, to examine the relationship between anxiety disorders and physical conditions. METHODS: The German Health Survey (N = 4181; response rate, 87.6%; ages 18-65 years) used the Composite International Diagnostic Interview to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition mood, substance use, and anxiety disorders (panic disorder, social phobia, specific phobia, generalized anxiety disorder, agoraphobia, obsessive-compulsive disorder) and a standardized medical interview supplemented by laboratory data to assess a broad range of physical conditions. The Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) was used to measure health-related quality of life. Number of days of role impairment was used to measure past 30-day disability. RESULTS: After adjusting for sociodemographic factors and other common mental disorders, the presence of an anxiety disorder was significantly associated with thyroid disease, respiratory disease, gastrointestinal disease, arthritis, migraine headaches, and allergic conditions (adjusted odds ratios between 1.39 and 2.12; P<.05). Compared with physical disorders alone, the presence of comorbid anxiety disorder with 1 or more physical disorders was associated with poorer physical component scores on the SF-36 (adjusted mean scores for physical condition alone and physical condition with anxiety disorder, 48.50 and 45.86, respectively; P<.001) and past 30-day disability due to physical problems (adjusted odds ratio, 1.69; 95% confidence interval, 1.20-2.37). CONCLUSION: Anxiety disorders are independently associated with several physical conditions in the community, and this comorbidity is significantly associated with poor quality of life and disability. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/17060541/Disability_and_poor_quality_of_life_associated_with_comorbid_anxiety_disorders_and_physical_conditions_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/archinte.166.19.2109 DB - PRIME DP - Unbound Medicine ER -