Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls.
J Org Chem. 2006 Oct 27; 71(22):8629-32.JO

Abstract

Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of sterically encumbered aryl-substituted ynamides with various diynes are described here. These cycloadditions provide the synthesis of an array of new chiral amide-substituted biaryls that can be useful in future chiral ligand designs.

Authors+Show Affiliations

Tracey MR

Division of Pharmaceutical Sciences and Department of Chemistry, Rennebohm Hall, 777 Highland Avenue, University of Wisconsin, Madison, Wisconsin 53705, USA.

Oppenheimer J

No affiliation info available

Hsung RP

No affiliation info available

MeSH

AlkynesAmidesCatalysisCyclizationMolecular StructureRhodiumStereoisomerism

Pub Type(s)

Journal Article

Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17064045

Citation

Tracey, Michael R., et al. "Rhodium(I)-catalyzed [2 + 2 + 2] Cycloadditions of Ynamides in the Synthesis of Amide-substituted Chiral Biaryls." The Journal of Organic Chemistry, vol. 71, no. 22, 2006, pp. 8629-32.

Tracey MR, Oppenheimer J, Hsung RP. Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls. J Org Chem. 2006;71(22):8629-32.

Tracey, M. R., Oppenheimer, J., & Hsung, R. P. (2006). Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls. The Journal of Organic Chemistry, 71(22), 8629-32.

Tracey MR, Oppenheimer J, Hsung RP. Rhodium(I)-catalyzed [2 + 2 + 2] Cycloadditions of Ynamides in the Synthesis of Amide-substituted Chiral Biaryls. J Org Chem. 2006 Oct 27;71(22):8629-32. PubMed PMID: 17064045.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls. AU - Tracey,Michael R, AU - Oppenheimer,Jossian, AU - Hsung,Richard P, PY - 2006/10/27/pubmed PY - 2007/8/19/medline PY - 2006/10/27/entrez SP - 8629 EP - 32 JF - The Journal of organic chemistry JO - J Org Chem VL - 71 IS - 22 N2 - Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of sterically encumbered aryl-substituted ynamides with various diynes are described here. These cycloadditions provide the synthesis of an array of new chiral amide-substituted biaryls that can be useful in future chiral ligand designs. SN - 0022-3263 UR - https://www.unboundmedicine.com/medline/citation/17064045/Rhodium_I__catalyzed_[2_+_2_+_2]_cycloadditions_of_ynamides_in_the_synthesis_of_amide_substituted_chiral_biaryls_ L2 - https://doi.org/10.1021/jo061683p DB - PRIME DP - Unbound Medicine ER -

Tags

Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls.J Org Chem. 2006 Oct 27; 71(22):8629-32.JO