Tags

Type your tag names separated by a space and hit enter

Overweight hypothesis in asthma and eczema in young adolescents.
Allergol Immunopathol (Madr). 2006 Sep-Oct; 34(5):199-205.AI

Abstract

BACKGROUND

A positive association between body mass index (BMI) and allergic diseases has recently been suggested; however the sex-dependence of this association remains controversial. The aim of the present study was to explore the relationship between BMI and asthma and eczema, as well as its sex-dependence in young adolescents.

METHODS

Self-reported data obtained through the standardized International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three written questionnaires of 2926 young adolescents aged 13-14 years old from randomly selected schools in Skopje (Republic of Macedonia) were used. The BMI for each individual was calculated and used-both unadjusted and adjusted for confounding factors-as a variable for analysis. The international cut-off points for BMI for overweight and obesity by sex and age were used. Because of the very low prevalence of obesity (1.5 %), obese respondents were included in the overweight group. The data were statistically analyzed by the chi-square test, the t-test for independent samples and odds ratios (OR, 95 % CI) in binary logistic regression.

RESULTS

Being overweight was significantly associated with an increased risk of having a dry night cough without a cold or chest infection (adjusted OR: 1.54; 95 % CI: 1.09-2.16; p = 0.01) and with having had self-reported asthma at some time (adjusted OR: 2.36; 95 % CI: 1.02-5.44; p = 0.04) in boys only. A significant association between overweight and other symptoms of asthma or atopic eczema was not established.

CONCLUSION

These findings suggest a male-specific positive association between overweight and a current dry night cough and having received a diagnosis of asthma at some time. No association was found with other asthma symptoms or atopic eczema in young adolescents.

Authors+Show Affiliations

Department of Pulmonology and Allergology, University Children's Hospital, Skopje, R. Macedonia. vlaskie@sonet.com.mkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17064649

Citation

Vlaski, E, et al. "Overweight Hypothesis in Asthma and Eczema in Young Adolescents." Allergologia Et Immunopathologia, vol. 34, no. 5, 2006, pp. 199-205.
Vlaski E, Stavric K, Isjanovska R, et al. Overweight hypothesis in asthma and eczema in young adolescents. Allergol Immunopathol (Madr). 2006;34(5):199-205.
Vlaski, E., Stavric, K., Isjanovska, R., Seckova, L., & Kimovska, M. (2006). Overweight hypothesis in asthma and eczema in young adolescents. Allergologia Et Immunopathologia, 34(5), 199-205.
Vlaski E, et al. Overweight Hypothesis in Asthma and Eczema in Young Adolescents. Allergol Immunopathol (Madr). 2006 Sep-Oct;34(5):199-205. PubMed PMID: 17064649.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Overweight hypothesis in asthma and eczema in young adolescents. AU - Vlaski,E, AU - Stavric,K, AU - Isjanovska,R, AU - Seckova,L, AU - Kimovska,M, PY - 2006/10/27/pubmed PY - 2007/3/10/medline PY - 2006/10/27/entrez SP - 199 EP - 205 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 34 IS - 5 N2 - BACKGROUND: A positive association between body mass index (BMI) and allergic diseases has recently been suggested; however the sex-dependence of this association remains controversial. The aim of the present study was to explore the relationship between BMI and asthma and eczema, as well as its sex-dependence in young adolescents. METHODS: Self-reported data obtained through the standardized International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three written questionnaires of 2926 young adolescents aged 13-14 years old from randomly selected schools in Skopje (Republic of Macedonia) were used. The BMI for each individual was calculated and used-both unadjusted and adjusted for confounding factors-as a variable for analysis. The international cut-off points for BMI for overweight and obesity by sex and age were used. Because of the very low prevalence of obesity (1.5 %), obese respondents were included in the overweight group. The data were statistically analyzed by the chi-square test, the t-test for independent samples and odds ratios (OR, 95 % CI) in binary logistic regression. RESULTS: Being overweight was significantly associated with an increased risk of having a dry night cough without a cold or chest infection (adjusted OR: 1.54; 95 % CI: 1.09-2.16; p = 0.01) and with having had self-reported asthma at some time (adjusted OR: 2.36; 95 % CI: 1.02-5.44; p = 0.04) in boys only. A significant association between overweight and other symptoms of asthma or atopic eczema was not established. CONCLUSION: These findings suggest a male-specific positive association between overweight and a current dry night cough and having received a diagnosis of asthma at some time. No association was found with other asthma symptoms or atopic eczema in young adolescents. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/17064649/Overweight_hypothesis_in_asthma_and_eczema_in_young_adolescents_ L2 - http://www.elsevier.es/en/linksolver/ft/ivp/0301-0546/34/199 DB - PRIME DP - Unbound Medicine ER -