Tags

Type your tag names separated by a space and hit enter

Determination of fluoride in toothpaste using headspace solid-phase microextraction and gas chromatography-flame ionization detection.
J Chromatogr A. 2007 May 25; 1150(1-2):173-7.JC

Abstract

A new method for determination of fluoride in toothpaste employing the headspace solid-phase microextraction (HS-SPME) followed by gas chromatography/flame ionization detection (GC/FID) has been proposed. It is a development of the method for determination of fluoride using trimethylchlorosilane (TMCS) as the derivatization reagent to form trimethylfluorosilane (TMFS), with the liquid/liquid extraction (LLE) step replaced by HS-SPME. To introduce the latter, it was necessary to determine the conditions of the reaction and to optimize the two stages of the SPME procedure: extraction and desorption. The parameters of the SPME analysis using carboxen/polydimethylsiloxane (CAR/PDMS) fiber were defined and compared with the corresponding ones for the LLE method, used as a reference. Also, these two methods were compared with respect to their linearity, precision, and accuracy. Results from toothpaste analyses using these two methods were highly correlated, indicating the potential to use the SPME extraction as an inexpensive and solventfree alternative to the LLE method.

Authors+Show Affiliations

Department of Chemistry and Environmental Protection, Faculty of Chemical Technology and Engineering, University of Technology and Agriculture in Bydgoszcz, Seminaryjna 3 St., 85-326 Bydgoszcz, Poland.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17070826

Citation

Wejnerowska, Grazyna, et al. "Determination of Fluoride in Toothpaste Using Headspace Solid-phase Microextraction and Gas Chromatography-flame Ionization Detection." Journal of Chromatography. A, vol. 1150, no. 1-2, 2007, pp. 173-7.
Wejnerowska G, Karczmarek A, Gaca J. Determination of fluoride in toothpaste using headspace solid-phase microextraction and gas chromatography-flame ionization detection. J Chromatogr A. 2007;1150(1-2):173-7.
Wejnerowska, G., Karczmarek, A., & Gaca, J. (2007). Determination of fluoride in toothpaste using headspace solid-phase microextraction and gas chromatography-flame ionization detection. Journal of Chromatography. A, 1150(1-2), 173-7.
Wejnerowska G, Karczmarek A, Gaca J. Determination of Fluoride in Toothpaste Using Headspace Solid-phase Microextraction and Gas Chromatography-flame Ionization Detection. J Chromatogr A. 2007 May 25;1150(1-2):173-7. PubMed PMID: 17070826.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Determination of fluoride in toothpaste using headspace solid-phase microextraction and gas chromatography-flame ionization detection. AU - Wejnerowska,Grazyna, AU - Karczmarek,Anna, AU - Gaca,Jerzy, Y1 - 2006/10/30/ PY - 2006/06/16/received PY - 2006/10/09/revised PY - 2006/10/13/accepted PY - 2006/10/31/pubmed PY - 2007/7/6/medline PY - 2006/10/31/entrez SP - 173 EP - 7 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1150 IS - 1-2 N2 - A new method for determination of fluoride in toothpaste employing the headspace solid-phase microextraction (HS-SPME) followed by gas chromatography/flame ionization detection (GC/FID) has been proposed. It is a development of the method for determination of fluoride using trimethylchlorosilane (TMCS) as the derivatization reagent to form trimethylfluorosilane (TMFS), with the liquid/liquid extraction (LLE) step replaced by HS-SPME. To introduce the latter, it was necessary to determine the conditions of the reaction and to optimize the two stages of the SPME procedure: extraction and desorption. The parameters of the SPME analysis using carboxen/polydimethylsiloxane (CAR/PDMS) fiber were defined and compared with the corresponding ones for the LLE method, used as a reference. Also, these two methods were compared with respect to their linearity, precision, and accuracy. Results from toothpaste analyses using these two methods were highly correlated, indicating the potential to use the SPME extraction as an inexpensive and solventfree alternative to the LLE method. SN - 0021-9673 UR - https://www.unboundmedicine.com/medline/citation/17070826/Determination_of_fluoride_in_toothpaste_using_headspace_solid_phase_microextraction_and_gas_chromatography_flame_ionization_detection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(06)01961-3 DB - PRIME DP - Unbound Medicine ER -