Tags

Type your tag names separated by a space and hit enter

Impact of diuron on aneuploidy and hemocyte parameters in Pacific oyster, Crassostrea gigas.
Arch Environ Contam Toxicol. 2007 Jan; 52(1):58-63.AE

Abstract

Diuron is a substituted urea herbicide used for agricultural and nonagricultural weed control. Its widespread use and relatively slow breakdown led us to analyze its influence on aneuploidy level (lowered chromosome number in a percentage of somatic cells) and hemocyte parameters in Pacific oysters, Crassostrea gigas. Adult oysters were subjected to two diuron concentrations (300 ng L(-1) and 3 microg L(-1)) for 11 weeks. Significantly higher aneuploidy level was observed in diuron-treated oysters compared with the control. Furthermore, the observed impact on aneuploidy persisted to the next generation as offspring exhibited significantly higher aneuploidy levels when their parents had been exposed to diuron. Significant increases in hemocyte parameters (cell mortality, phagocytosis, granulocyte percentage, reactive oxygen species, and lysosome presence) of the adults were also observed after 4 weeks of diuron exposure. The effects observed on oyster aneuploidy level and hemocyte parameters could have serious environmental and practical consequences.

Authors+Show Affiliations

IFREMER, Laboratoire de Génétique et Pathologie, 17390, La Tremblade, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17072671

Citation

Bouilly, Karine, et al. "Impact of Diuron On Aneuploidy and Hemocyte Parameters in Pacific Oyster, Crassostrea Gigas." Archives of Environmental Contamination and Toxicology, vol. 52, no. 1, 2007, pp. 58-63.
Bouilly K, Bonnard M, Gagnaire B, et al. Impact of diuron on aneuploidy and hemocyte parameters in Pacific oyster, Crassostrea gigas. Arch Environ Contam Toxicol. 2007;52(1):58-63.
Bouilly, K., Bonnard, M., Gagnaire, B., Renault, T., & Lapègue, S. (2007). Impact of diuron on aneuploidy and hemocyte parameters in Pacific oyster, Crassostrea gigas. Archives of Environmental Contamination and Toxicology, 52(1), 58-63.
Bouilly K, et al. Impact of Diuron On Aneuploidy and Hemocyte Parameters in Pacific Oyster, Crassostrea Gigas. Arch Environ Contam Toxicol. 2007;52(1):58-63. PubMed PMID: 17072671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of diuron on aneuploidy and hemocyte parameters in Pacific oyster, Crassostrea gigas. AU - Bouilly,Karine, AU - Bonnard,Marc, AU - Gagnaire,Béatrice, AU - Renault,Tristan, AU - Lapègue,Sylvie, Y1 - 2006/10/26/ PY - 2005/10/21/received PY - 2006/05/29/accepted PY - 2006/10/31/pubmed PY - 2007/2/13/medline PY - 2006/10/31/entrez SP - 58 EP - 63 JF - Archives of environmental contamination and toxicology JO - Arch Environ Contam Toxicol VL - 52 IS - 1 N2 - Diuron is a substituted urea herbicide used for agricultural and nonagricultural weed control. Its widespread use and relatively slow breakdown led us to analyze its influence on aneuploidy level (lowered chromosome number in a percentage of somatic cells) and hemocyte parameters in Pacific oysters, Crassostrea gigas. Adult oysters were subjected to two diuron concentrations (300 ng L(-1) and 3 microg L(-1)) for 11 weeks. Significantly higher aneuploidy level was observed in diuron-treated oysters compared with the control. Furthermore, the observed impact on aneuploidy persisted to the next generation as offspring exhibited significantly higher aneuploidy levels when their parents had been exposed to diuron. Significant increases in hemocyte parameters (cell mortality, phagocytosis, granulocyte percentage, reactive oxygen species, and lysosome presence) of the adults were also observed after 4 weeks of diuron exposure. The effects observed on oyster aneuploidy level and hemocyte parameters could have serious environmental and practical consequences. SN - 0090-4341 UR - https://www.unboundmedicine.com/medline/citation/17072671/Impact_of_diuron_on_aneuploidy_and_hemocyte_parameters_in_Pacific_oyster_Crassostrea_gigas_ L2 - https://dx.doi.org/10.1007/s00244-005-0256-8 DB - PRIME DP - Unbound Medicine ER -