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Surface-enhanced Raman scattering-based nanoprobe for high-resolution, non-scanning chemical imaging.
Anal Chem. 2006 Nov 01; 78(21):7535-46.AC

Abstract

This work describes the development and demonstration of a non-scanning chemical imaging probe, capable of obtaining surface-enhanced Raman scattering (SERS) images of samples with which it is in direct contact. The SERS imaging arrays (i.e., nanoprobes) are used in a signal collection mode to obtain images by measuring as many as 30 000 individual sub-diffraction-limited locations on a sample's surface simultaneously. These SERS probes are fabricated from coherent fiber-optic imaging bundles, allowing for the formation of a highly ordered roughened metal surface, capable of providing uniform SERS enhancement (<2.0% relative standard deviation) across the entire imaging surface. These optimized SERS nanoprobes have potential application to a wide range of research fields from materials science to cellular biology.

Authors+Show Affiliations

Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, Maryland 21250, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

17073424

Citation

Hankus, Mikella E., et al. "Surface-enhanced Raman Scattering-based Nanoprobe for High-resolution, Non-scanning Chemical Imaging." Analytical Chemistry, vol. 78, no. 21, 2006, pp. 7535-46.
Hankus ME, Li H, Gibson GJ, et al. Surface-enhanced Raman scattering-based nanoprobe for high-resolution, non-scanning chemical imaging. Anal Chem. 2006;78(21):7535-46.
Hankus, M. E., Li, H., Gibson, G. J., & Cullum, B. M. (2006). Surface-enhanced Raman scattering-based nanoprobe for high-resolution, non-scanning chemical imaging. Analytical Chemistry, 78(21), 7535-46.
Hankus ME, et al. Surface-enhanced Raman Scattering-based Nanoprobe for High-resolution, Non-scanning Chemical Imaging. Anal Chem. 2006 Nov 1;78(21):7535-46. PubMed PMID: 17073424.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surface-enhanced Raman scattering-based nanoprobe for high-resolution, non-scanning chemical imaging. AU - Hankus,Mikella E, AU - Li,Honggang, AU - Gibson,Gregory J, AU - Cullum,Brian M, PY - 2006/11/1/pubmed PY - 2007/4/20/medline PY - 2006/11/1/entrez SP - 7535 EP - 46 JF - Analytical chemistry JO - Anal Chem VL - 78 IS - 21 N2 - This work describes the development and demonstration of a non-scanning chemical imaging probe, capable of obtaining surface-enhanced Raman scattering (SERS) images of samples with which it is in direct contact. The SERS imaging arrays (i.e., nanoprobes) are used in a signal collection mode to obtain images by measuring as many as 30 000 individual sub-diffraction-limited locations on a sample's surface simultaneously. These SERS probes are fabricated from coherent fiber-optic imaging bundles, allowing for the formation of a highly ordered roughened metal surface, capable of providing uniform SERS enhancement (<2.0% relative standard deviation) across the entire imaging surface. These optimized SERS nanoprobes have potential application to a wide range of research fields from materials science to cellular biology. SN - 0003-2700 UR - https://www.unboundmedicine.com/medline/citation/17073424/Surface_enhanced_Raman_scattering_based_nanoprobe_for_high_resolution_non_scanning_chemical_imaging_ L2 - https://doi.org/10.1021/ac061125a DB - PRIME DP - Unbound Medicine ER -