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[Aids-related toxoplasma-encephalitis presenting with acute psychotic episode].

Abstract

The most frequent neurological manifestations of the Acquired Immunodeficiency Syndrome-(AIDS) are Cerebral Toxoplasmosis, Primary Central Nervous System Lymphoma (PCNSL), Progressive Multifocal Leukoencephalopathy (PML) and AIDS-encephalitis (AIDS-dementia complex, multinucleated giant cell encephalitis, HIV-encephalopathy). Neurological complications usually occur in the advanced stages of the disease, and they are uncommon in the beginning as presenting illness, but may result in life-threatening condition or in death. Rarely the disease presents as a neuropsychiatric illness in an undiagnosed AIDS patient, delaying a proper diagnosis. We present the case of a 34 years old patient treated for AIDS-related Toxoplasma-encephalitis in our department. His illness started as an acute psychosis followed by rapid mental and somatic decline, leading to death in three months. His HIV-seropositivity was not known at his admission, and the extraneural manifestations were slight. The diagnosis was established by serology, imaging methods and histopathological investigation. After presenting the medical history and results of autopsy studies of the patient we discuss the problems of the differential diagnosis, especially regarding the findings of the imaging methods.

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Authors+Show Affiliations

,

Semmelweis Egyetem, Altalános Orvostudományi Kar, Neurológiai Klinika, Budapest. sandor@neur.sote.hu

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Source

Ideggyogyaszati szemle 59:7-8 2006 Jul 20 pg 289-93

MeSH

AIDS-Related Opportunistic Infections
Adult
Animals
Antibodies, Viral
Atrophy
Autopsy
Brain
Epstein-Barr Virus Infections
Fatal Outcome
HIV Seropositivity
Herpesvirus 4, Human
Homosexuality, Male
Humans
Magnetic Resonance Imaging
Male
Tomography, X-Ray Computed
Toxoplasma
Toxoplasmosis, Cerebral

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

hun

PubMed ID

17076307

Citation

Ilniczky, Sándor, et al. "[Aids-related Toxoplasma-encephalitis Presenting With Acute Psychotic Episode]." Ideggyogyaszati Szemle, vol. 59, no. 7-8, 2006, pp. 289-93.
Ilniczky S, Debreczeni R, Kovács T, et al. [Aids-related toxoplasma-encephalitis presenting with acute psychotic episode]. Ideggyogy Sz. 2006;59(7-8):289-93.
Ilniczky, S., Debreczeni, R., Kovács, T., Várkonyi, V., Barsi, P., & Szirmai, I. (2006). [Aids-related toxoplasma-encephalitis presenting with acute psychotic episode]. Ideggyogyaszati Szemle, 59(7-8), pp. 289-93.
Ilniczky S, et al. [Aids-related Toxoplasma-encephalitis Presenting With Acute Psychotic Episode]. Ideggyogy Sz. 2006 Jul 20;59(7-8):289-93. PubMed PMID: 17076307.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Aids-related toxoplasma-encephalitis presenting with acute psychotic episode]. AU - Ilniczky,Sándor, AU - Debreczeni,Róbert, AU - Kovács,Tibor, AU - Várkonyi,Viktória, AU - Barsi,Péter, AU - Szirmai,Imre, PY - 2006/11/2/pubmed PY - 2007/3/31/medline PY - 2006/11/2/entrez SP - 289 EP - 93 JF - Ideggyogyaszati szemle JO - Ideggyogy Sz VL - 59 IS - 7-8 N2 - The most frequent neurological manifestations of the Acquired Immunodeficiency Syndrome-(AIDS) are Cerebral Toxoplasmosis, Primary Central Nervous System Lymphoma (PCNSL), Progressive Multifocal Leukoencephalopathy (PML) and AIDS-encephalitis (AIDS-dementia complex, multinucleated giant cell encephalitis, HIV-encephalopathy). Neurological complications usually occur in the advanced stages of the disease, and they are uncommon in the beginning as presenting illness, but may result in life-threatening condition or in death. Rarely the disease presents as a neuropsychiatric illness in an undiagnosed AIDS patient, delaying a proper diagnosis. We present the case of a 34 years old patient treated for AIDS-related Toxoplasma-encephalitis in our department. His illness started as an acute psychosis followed by rapid mental and somatic decline, leading to death in three months. His HIV-seropositivity was not known at his admission, and the extraneural manifestations were slight. The diagnosis was established by serology, imaging methods and histopathological investigation. After presenting the medical history and results of autopsy studies of the patient we discuss the problems of the differential diagnosis, especially regarding the findings of the imaging methods. SN - 0019-1442 UR - https://www.unboundmedicine.com/medline/citation/17076307/[Aids_related_toxoplasma_encephalitis_presenting_with_acute_psychotic_episode]_ L2 - http://www.diseaseinfosearch.org/result/279 DB - PRIME DP - Unbound Medicine ER -