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[Medical management of patients with atypical degenerative parkinsonian syndromes].
Rev Neurol (Paris). 2006 Nov; 162(11):1147-58.RN

Abstract

Atypical degenerative parkinsonian syndromes (progressive supranuclar palsy, multiple system atrophy, corticobasal degeneration, Lewy body dementia) are an important differential diagnosis to idiopathic Parkinson's disease. However, because these disorders are characterized by the degeneration of multiple neuronal populations, treatment approaches are much less specific than in Parkinson's disease, where dopamimetic drugs represent the mainstay of therapy. Thus, and because the progression of these disorders is usually more aggressive than Parkinson's disease, many physicians face a form of therapeutic resignation when confronted with patients suffering from atypical degenerative parkinsonian syndromes. However, in the present article, we wish to show that a symptom-by-symptom approach can substantially relieve the patients and their caregivers by providing an overview of pharmacologic and non-pharmacologic treatment options.

Authors+Show Affiliations

Centre d'Investigation Clinique et INSERM U 679, Hôpital de la Salpêtrière, et Université Pierre et Marie Curie, Faculté de Médecine, Paris. hartmann@ccr.jussieu.frNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

17086154

Citation

Chastan, N, and A Hartmann. "[Medical Management of Patients With Atypical Degenerative Parkinsonian Syndromes]." Revue Neurologique, vol. 162, no. 11, 2006, pp. 1147-58.
Chastan N, Hartmann A. [Medical management of patients with atypical degenerative parkinsonian syndromes]. Rev Neurol (Paris). 2006;162(11):1147-58.
Chastan, N., & Hartmann, A. (2006). [Medical management of patients with atypical degenerative parkinsonian syndromes]. Revue Neurologique, 162(11), 1147-58.
Chastan N, Hartmann A. [Medical Management of Patients With Atypical Degenerative Parkinsonian Syndromes]. Rev Neurol (Paris). 2006;162(11):1147-58. PubMed PMID: 17086154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Medical management of patients with atypical degenerative parkinsonian syndromes]. AU - Chastan,N, AU - Hartmann,A, PY - 2006/11/7/pubmed PY - 2006/12/21/medline PY - 2006/11/7/entrez SP - 1147 EP - 58 JF - Revue neurologique JO - Rev Neurol (Paris) VL - 162 IS - 11 N2 - Atypical degenerative parkinsonian syndromes (progressive supranuclar palsy, multiple system atrophy, corticobasal degeneration, Lewy body dementia) are an important differential diagnosis to idiopathic Parkinson's disease. However, because these disorders are characterized by the degeneration of multiple neuronal populations, treatment approaches are much less specific than in Parkinson's disease, where dopamimetic drugs represent the mainstay of therapy. Thus, and because the progression of these disorders is usually more aggressive than Parkinson's disease, many physicians face a form of therapeutic resignation when confronted with patients suffering from atypical degenerative parkinsonian syndromes. However, in the present article, we wish to show that a symptom-by-symptom approach can substantially relieve the patients and their caregivers by providing an overview of pharmacologic and non-pharmacologic treatment options. SN - 0035-3787 UR - https://www.unboundmedicine.com/medline/citation/17086154/[Medical_management_of_patients_with_atypical_degenerative_parkinsonian_syndromes]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/MDOI-RN-11-2006-162-11-0035-3787-101019-200605403 DB - PRIME DP - Unbound Medicine ER -