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Free radical-scavenging delta-lactones from Boletus calopus.
Planta Med. 2006 Dec; 72(15):1431-2.PM

Abstract

The methanol extracts from the fruiting body of the mushroom Boletus calopus showed free radical-scavenging activity. Bioactivity-guided fractionation of the methanol extracts led to a new hydroxylated calopin named calopin B, along with the known delta-lactones calopin and cyclocalopin A. The structure of the new calopin analogue was elucidated by spectroscopic methods. All compounds showed potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC (50) values of 1.2 - 5.4 microg/mL.

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Authors+Show Affiliations

Kim JW
Functional Metabolomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Yoo ID
No affiliation info available
Kim WG
No affiliation info available

MeSH

AgaricalesBenzothiazolesBiphenyl CompoundsFree Radical ScavengersHumansInhibitory Concentration 50LactonesPhytotherapyPicratesPlant ExtractsStructure-Activity RelationshipSulfonic AcidsSuperoxides

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17091435

Citation

Kim, Jin-Woo, et al. "Free Radical-scavenging Delta-lactones From Boletus Calopus." Planta Medica, vol. 72, no. 15, 2006, pp. 1431-2.
Kim JW, Yoo ID, Kim WG. Free radical-scavenging delta-lactones from Boletus calopus. Planta Med. 2006;72(15):1431-2.
Kim, J. W., Yoo, I. D., & Kim, W. G. (2006). Free radical-scavenging delta-lactones from Boletus calopus. Planta Medica, 72(15), 1431-2.
Kim JW, Yoo ID, Kim WG. Free Radical-scavenging Delta-lactones From Boletus Calopus. Planta Med. 2006;72(15):1431-2. PubMed PMID: 17091435.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Free radical-scavenging delta-lactones from Boletus calopus. AU - Kim,Jin-Woo, AU - Yoo,Ick-Dong, AU - Kim,Won-Gon, Y1 - 2006/11/07/ PY - 2006/11/9/pubmed PY - 2007/3/6/medline PY - 2006/11/9/entrez SP - 1431 EP - 2 JF - Planta medica JO - Planta Med VL - 72 IS - 15 N2 - The methanol extracts from the fruiting body of the mushroom Boletus calopus showed free radical-scavenging activity. Bioactivity-guided fractionation of the methanol extracts led to a new hydroxylated calopin named calopin B, along with the known delta-lactones calopin and cyclocalopin A. The structure of the new calopin analogue was elucidated by spectroscopic methods. All compounds showed potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC (50) values of 1.2 - 5.4 microg/mL. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/17091435/Free_radical_scavenging_delta_lactones_from_Boletus_calopus_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-951722 DB - PRIME DP - Unbound Medicine ER -