Tags

Type your tag names separated by a space and hit enter

Prevalence and clinical presentations of atypical pathogens infection in community acquired pneumonia in Thailand.
J Med Assoc Thai. 2006 Sep; 89(9):1412-9.JM

Abstract

OBJECTIVES

To determine the prevalence of atypical pneumonia and clinical presentations in patients with community acquired pneumonia (CAP).

MATERIAL AND METHOD

A prospective multi-centered study was performed in patients aged > or = 2 years with the diagnosis of CAP who were treated at seven governmental hospitals in Bangkok from December 2001 to November 2002. The diagnosis of current infection was based on > or = 4 fold rise in antibody sera or persistently high antibody titers together with the presence of DNA of M. pneumoniae or C. pneumoniae in respiratory secretion or antigen of L. pneumophila in the urine. Clinical presentations were compared between patients with atypical pneumonia and unspecified pneumonia.

RESULTS

Of 292 patients, 18.8% had current infection with atypical respiratory pathogens (M. pneumoniae 14.0%, C. pneumoniae 3.4%, L. pneumophila 0.4% and mixed infection 1.0%). Only age at presentation was significantly associated with atypical pneumonia in adults, while absence of dyspnea, lobar consolidation, and age > or = 5 years were significant findings for atypical pneumonia in children.

CONCLUSION

The present study confirms the significance of atypical pathogens in adults and children. Moreover lobar consolidation is likely to predict atypical pneumonia in childhood CAP.

Authors+Show Affiliations

Prapphal N
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Rama IV Rd, Bangkok 10330, Thailand. fmednph@md2.md.chula.ac.th
Suwanjutha S
No affiliation info available
Durongkaveroj P
No affiliation info available
Lochindarat S
No affiliation info available
Kunakorn M
No affiliation info available
Deerojanawong J
No affiliation info available
Chantarojanasiri T
No affiliation info available
Supanitayaonon Y
No affiliation info available
Janedittakarn P
No affiliation info available

MeSH

AdolescentAdultChildChild, PreschoolChlamydophila pneumoniaeCommunity-Acquired InfectionsFemaleHumansLegionella pneumophilaMaleMiddle AgedMycoplasma pneumoniaePneumoniaPneumonia, MycoplasmaPrevalenceThailand

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17100378

Citation

Prapphal, Nuanchan, et al. "Prevalence and Clinical Presentations of Atypical Pathogens Infection in Community Acquired Pneumonia in Thailand." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 89, no. 9, 2006, pp. 1412-9.
Prapphal N, Suwanjutha S, Durongkaveroj P, et al. Prevalence and clinical presentations of atypical pathogens infection in community acquired pneumonia in Thailand. J Med Assoc Thai. 2006;89(9):1412-9.
Prapphal, N., Suwanjutha, S., Durongkaveroj, P., Lochindarat, S., Kunakorn, M., Deerojanawong, J., Chantarojanasiri, T., Supanitayaonon, Y., & Janedittakarn, P. (2006). Prevalence and clinical presentations of atypical pathogens infection in community acquired pneumonia in Thailand. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 89(9), 1412-9.
Prapphal N, et al. Prevalence and Clinical Presentations of Atypical Pathogens Infection in Community Acquired Pneumonia in Thailand. J Med Assoc Thai. 2006;89(9):1412-9. PubMed PMID: 17100378.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and clinical presentations of atypical pathogens infection in community acquired pneumonia in Thailand. AU - Prapphal,Nuanchan, AU - Suwanjutha,Subharee, AU - Durongkaveroj,Pravin, AU - Lochindarat,Sorasak, AU - Kunakorn,Mongkol, AU - Deerojanawong,Jitladda, AU - Chantarojanasiri,Teerachai, AU - Supanitayaonon,Yingsak, AU - Janedittakarn,Pisit, PY - 2006/11/15/pubmed PY - 2007/1/24/medline PY - 2006/11/15/entrez SP - 1412 EP - 9 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 89 IS - 9 N2 - OBJECTIVES: To determine the prevalence of atypical pneumonia and clinical presentations in patients with community acquired pneumonia (CAP). MATERIAL AND METHOD: A prospective multi-centered study was performed in patients aged > or = 2 years with the diagnosis of CAP who were treated at seven governmental hospitals in Bangkok from December 2001 to November 2002. The diagnosis of current infection was based on > or = 4 fold rise in antibody sera or persistently high antibody titers together with the presence of DNA of M. pneumoniae or C. pneumoniae in respiratory secretion or antigen of L. pneumophila in the urine. Clinical presentations were compared between patients with atypical pneumonia and unspecified pneumonia. RESULTS: Of 292 patients, 18.8% had current infection with atypical respiratory pathogens (M. pneumoniae 14.0%, C. pneumoniae 3.4%, L. pneumophila 0.4% and mixed infection 1.0%). Only age at presentation was significantly associated with atypical pneumonia in adults, while absence of dyspnea, lobar consolidation, and age > or = 5 years were significant findings for atypical pneumonia in children. CONCLUSION: The present study confirms the significance of atypical pathogens in adults and children. Moreover lobar consolidation is likely to predict atypical pneumonia in childhood CAP. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/17100378/Prevalence_and_clinical_presentations_of_atypical_pathogens_infection_in_community_acquired_pneumonia_in_Thailand_ L2 - https://medlineplus.gov/pneumonia.html DB - PRIME DP - Unbound Medicine ER -