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Use of alcohol and drugs to self-medicate anxiety disorders in a nationally representative sample.
J Nerv Ment Dis. 2006 Nov; 194(11):818-25.JN

Abstract

This study examined the prevalence and correlates of self-medication of anxiety disorders with alcohol and drugs in a nationally representative sample (N = 5877). A modified version of the Composite International Diagnostic Interview was used to make DSM-III-R mental disorder diagnoses. Frequencies of self-medication ranged from 7.9% (social phobia, speaking subtype) to 35.6% (generalized anxiety disorder). Among respondents with an anxiety disorder, self-medication was significantly associated with an increased likelihood of comorbid mood disorders, substance use disorders, distress, suicidal ideation, and suicide attempts. Self-medication behavior remained significantly associated with an increased likelihood of suicidal ideation (adjusted odds ratio = 1.66; 1.17-2.36) as well as suicide attempts (adjusted odds ratio = 2.23; 1.50-3.31), even after adjusting for a number of sociodemographic and psychiatric variables. These results suggest that individuals with anxiety disorders who self-medicate their symptoms with alcohol or drugs may be at increased risk for mood and substance use disorders and suicidal behavior.

Authors+Show Affiliations

Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17102705

Citation

Bolton, James, et al. "Use of Alcohol and Drugs to Self-medicate Anxiety Disorders in a Nationally Representative Sample." The Journal of Nervous and Mental Disease, vol. 194, no. 11, 2006, pp. 818-25.
Bolton J, Cox B, Clara I, et al. Use of alcohol and drugs to self-medicate anxiety disorders in a nationally representative sample. J Nerv Ment Dis. 2006;194(11):818-25.
Bolton, J., Cox, B., Clara, I., & Sareen, J. (2006). Use of alcohol and drugs to self-medicate anxiety disorders in a nationally representative sample. The Journal of Nervous and Mental Disease, 194(11), 818-25.
Bolton J, et al. Use of Alcohol and Drugs to Self-medicate Anxiety Disorders in a Nationally Representative Sample. J Nerv Ment Dis. 2006;194(11):818-25. PubMed PMID: 17102705.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Use of alcohol and drugs to self-medicate anxiety disorders in a nationally representative sample. AU - Bolton,James, AU - Cox,Brian, AU - Clara,Ian, AU - Sareen,Jitender, PY - 2006/11/15/pubmed PY - 2006/12/12/medline PY - 2006/11/15/entrez SP - 818 EP - 25 JF - The Journal of nervous and mental disease JO - J. Nerv. Ment. Dis. VL - 194 IS - 11 N2 - This study examined the prevalence and correlates of self-medication of anxiety disorders with alcohol and drugs in a nationally representative sample (N = 5877). A modified version of the Composite International Diagnostic Interview was used to make DSM-III-R mental disorder diagnoses. Frequencies of self-medication ranged from 7.9% (social phobia, speaking subtype) to 35.6% (generalized anxiety disorder). Among respondents with an anxiety disorder, self-medication was significantly associated with an increased likelihood of comorbid mood disorders, substance use disorders, distress, suicidal ideation, and suicide attempts. Self-medication behavior remained significantly associated with an increased likelihood of suicidal ideation (adjusted odds ratio = 1.66; 1.17-2.36) as well as suicide attempts (adjusted odds ratio = 2.23; 1.50-3.31), even after adjusting for a number of sociodemographic and psychiatric variables. These results suggest that individuals with anxiety disorders who self-medicate their symptoms with alcohol or drugs may be at increased risk for mood and substance use disorders and suicidal behavior. SN - 0022-3018 UR - https://www.unboundmedicine.com/medline/citation/17102705/Use_of_alcohol_and_drugs_to_self_medicate_anxiety_disorders_in_a_nationally_representative_sample_ L2 - http://dx.doi.org/10.1097/01.nmd.0000244481.63148.98 DB - PRIME DP - Unbound Medicine ER -