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Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin.
Fitoterapia. 2007 Jan; 78(1):7-11.F

Abstract

Steam distilled essential oil from the aerial parts of Pogostemon cablin was analyzed by gas chromatography-mass spectrometry (GC-MS). Forty one compounds were identified of which alpha-guaiene (20.62%) and alpha-bulnesene (16.18%) were major constituents. Furthermore, fractionation of the essential oil from P. cablin guided by inhibitory activity against PAF-induced platelet aggregation led to the isolation of the sesquiterpene, alpha-bulnesene.

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Authors+Show Affiliations

Tsai YC
Institute of Biochemistry and Molecular Biology National Yang-Ming University, Taipei, Taiwan. tsaiyc@ym.edu.tw
Hsu HC
No affiliation info available
Yang WC
No affiliation info available
Tsai WJ
No affiliation info available
Chen CC
No affiliation info available
Watanabe T
No affiliation info available

MeSH

AnimalsLamiaceaeMaleMass SpectrometryPhytotherapyPlant Components, AerialPlant OilsPlatelet AggregationPlatelet Aggregation InhibitorsRabbitsSesquiterpenesSesquiterpenes, Guaiane

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17107759

Citation

Tsai, Ying-Chieh, et al. "Alpha-bulnesene, a PAF Inhibitor Isolated From the Essential Oil of Pogostemon Cablin." Fitoterapia, vol. 78, no. 1, 2007, pp. 7-11.
Tsai YC, Hsu HC, Yang WC, et al. Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin. Fitoterapia. 2007;78(1):7-11.
Tsai, Y. C., Hsu, H. C., Yang, W. C., Tsai, W. J., Chen, C. C., & Watanabe, T. (2007). Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin. Fitoterapia, 78(1), 7-11.
Tsai YC, et al. Alpha-bulnesene, a PAF Inhibitor Isolated From the Essential Oil of Pogostemon Cablin. Fitoterapia. 2007;78(1):7-11. PubMed PMID: 17107759.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin. AU - Tsai,Ying-Chieh, AU - Hsu,Hui-Chun, AU - Yang,Wen-Chia, AU - Tsai,Wei-Jern, AU - Chen,Chien-Chih, AU - Watanabe,Takashi, Y1 - 2006/09/23/ PY - 2005/05/25/received PY - 2006/09/06/accepted PY - 2006/11/17/pubmed PY - 2007/3/8/medline PY - 2006/11/17/entrez SP - 7 EP - 11 JF - Fitoterapia JO - Fitoterapia VL - 78 IS - 1 N2 - Steam distilled essential oil from the aerial parts of Pogostemon cablin was analyzed by gas chromatography-mass spectrometry (GC-MS). Forty one compounds were identified of which alpha-guaiene (20.62%) and alpha-bulnesene (16.18%) were major constituents. Furthermore, fractionation of the essential oil from P. cablin guided by inhibitory activity against PAF-induced platelet aggregation led to the isolation of the sesquiterpene, alpha-bulnesene. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/17107759/Alpha_bulnesene_a_PAF_inhibitor_isolated_from_the_essential_oil_of_Pogostemon_cablin_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(06)00224-3 DB - PRIME DP - Unbound Medicine ER -