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Clinical trial to compare tinnitus masking and tinnitus retraining therapy.

Abstract

CONCLUSION

Both tinnitus masking (TM) and tinnitus retraining therapy (TRT) can be effective therapies for amelioration of tinnitus. TM may be more effective for patients in the short term, but with continued treatment TRT may produce the greatest effects.

OBJECTIVES

Although TM and TRT have been used for many years, research has not documented definitively the efficacy of these methods. The present study was a controlled clinical trial to prospectively evaluate the clinical efficacy of these two methods for US military veterans with severe tinnitus.

SUBJECTS AND METHODS

Over 800 veterans were screened to ensure that enrolled patients had tinnitus of sufficient severity to justify 18 months of individualized treatment. Qualifying patients (n=123) were placed quasi-randomly (alternating placement) into treatment with either TM or TRT. Treatment was administered at 0, 3, 6, 12, and 18 months. Outcomes of treatment were evaluated primarily using three self-administered tinnitus questionnaires (Tinnitus Handicap Inventory, Tinnitus Handicap Questionnaire, Tinnitus Severity Index).

RESULTS

Findings are presented from the three written questionnaires with respect to three categories of patients: describing tinnitus as a 'moderate,' 'big,' and 'very big' problem at baseline. Based on effect sizes, both groups showed considerable improvement overall. In general, TM effects remained fairly constant over time while TRT effects improved incrementally. For the patients with a 'moderate' and 'big' problem, TM provided the greatest benefit at 3 and 6 months; benefit to these TRT patients was slightly greater at 12 months, and much greater at 18 months. For patients with a 'very big' problem, TM provided the greatest benefit at 3 months. For these latter patients, results were about the same between groups at 6 months, and improvement for TRT was much greater at 12 months, with further gains at 18 months.

Authors+Show Affiliations

VA RR&D National Center for Rehabilitative Auditory Research, VA Medical Center (VAMC), Portland, OR, USA. james.henry@med.va.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

17114146

Citation

Henry, J A., et al. "Clinical Trial to Compare Tinnitus Masking and Tinnitus Retraining Therapy." Acta Oto-laryngologica. Supplementum, 2006, pp. 64-9.
Henry JA, Schechter MA, Zaugg TL, et al. Clinical trial to compare tinnitus masking and tinnitus retraining therapy. Acta Otolaryngol Suppl. 2006.
Henry, J. A., Schechter, M. A., Zaugg, T. L., Griest, S., Jastreboff, P. J., Vernon, J. A., Kaelin, C., Meikle, M. B., Lyons, K. S., & Stewart, B. J. (2006). Clinical trial to compare tinnitus masking and tinnitus retraining therapy. Acta Oto-laryngologica. Supplementum, (556), 64-9.
Henry JA, et al. Clinical Trial to Compare Tinnitus Masking and Tinnitus Retraining Therapy. Acta Otolaryngol Suppl. 2006;(556)64-9. PubMed PMID: 17114146.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical trial to compare tinnitus masking and tinnitus retraining therapy. AU - Henry,J A, AU - Schechter,M A, AU - Zaugg,T L, AU - Griest,S, AU - Jastreboff,P J, AU - Vernon,J A, AU - Kaelin,C, AU - Meikle,M B, AU - Lyons,K S, AU - Stewart,B J, PY - 2006/11/23/pubmed PY - 2007/5/9/medline PY - 2006/11/23/entrez SP - 64 EP - 9 JF - Acta oto-laryngologica. Supplementum JO - Acta Otolaryngol Suppl IS - 556 N2 - CONCLUSION: Both tinnitus masking (TM) and tinnitus retraining therapy (TRT) can be effective therapies for amelioration of tinnitus. TM may be more effective for patients in the short term, but with continued treatment TRT may produce the greatest effects. OBJECTIVES: Although TM and TRT have been used for many years, research has not documented definitively the efficacy of these methods. The present study was a controlled clinical trial to prospectively evaluate the clinical efficacy of these two methods for US military veterans with severe tinnitus. SUBJECTS AND METHODS: Over 800 veterans were screened to ensure that enrolled patients had tinnitus of sufficient severity to justify 18 months of individualized treatment. Qualifying patients (n=123) were placed quasi-randomly (alternating placement) into treatment with either TM or TRT. Treatment was administered at 0, 3, 6, 12, and 18 months. Outcomes of treatment were evaluated primarily using three self-administered tinnitus questionnaires (Tinnitus Handicap Inventory, Tinnitus Handicap Questionnaire, Tinnitus Severity Index). RESULTS: Findings are presented from the three written questionnaires with respect to three categories of patients: describing tinnitus as a 'moderate,' 'big,' and 'very big' problem at baseline. Based on effect sizes, both groups showed considerable improvement overall. In general, TM effects remained fairly constant over time while TRT effects improved incrementally. For the patients with a 'moderate' and 'big' problem, TM provided the greatest benefit at 3 and 6 months; benefit to these TRT patients was slightly greater at 12 months, and much greater at 18 months. For patients with a 'very big' problem, TM provided the greatest benefit at 3 months. For these latter patients, results were about the same between groups at 6 months, and improvement for TRT was much greater at 12 months, with further gains at 18 months. SN - 0365-5237 UR - https://www.unboundmedicine.com/medline/citation/17114146/Clinical_trial_to_compare_tinnitus_masking_and_tinnitus_retraining_therapy_ L2 - http://www.diseaseinfosearch.org/result/9653 DB - PRIME DP - Unbound Medicine ER -