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Screening for depression and anxiety disorders in primary care patients.
Depress Anxiety. 2007; 24(7):455-60.DA

Abstract

Mood and anxiety disorders are highly prevalent in primary health care. In this study we assessed performance of the Hospital Anxiety and Depression Scale (HADS) for screening of depression and anxiety disorders in a population of primary care patients. A total of 503 primary care patients consecutively admitted to the primary care medical center in Kaunas, Lithuania, completed the study. We found that the HADS subscale of depression (HADS-D) at a cutoff score of 6 or more showed the best performance screening for a major depressive episode diagnosed by means of the Mini International Neuropsychiatric Interview (MINI), with a sensitivity of 80%, specificity of 69%, positive predictive value of 80%, negative predictive value of 92%, and area under the receiver operating characteristic (ROC) curve of 0.75. Performance of the HADS-D against MINI diagnosis of dysthymia was weak. The HADS subscale of anxiety (HADS-A) at a cutoff score of 9 or more showed the best performance screening for MINI diagnosis of overall anxiety disorders, with a sensitivity of 77%, specificity of 75%, positive predictive value of 53%, negative predictive value of 90%, and area under the ROC curve of 0.76. These results suggest that in primary care patients HADS is an adequate screening instrument for the MINI diagnoses of major depressive episode, but not for dysthymia at a cutoff score of 6, and for anxiety disorders at a cutoff score of 9.

Authors+Show Affiliations

Faculty of Medicine, Kaunas University of Medicine, Kaunas, Lithuania. a.bunevicius@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17117433

Citation

Bunevicius, Adomas, et al. "Screening for Depression and Anxiety Disorders in Primary Care Patients." Depression and Anxiety, vol. 24, no. 7, 2007, pp. 455-60.
Bunevicius A, Peceliuniene J, Mickuviene N, et al. Screening for depression and anxiety disorders in primary care patients. Depress Anxiety. 2007;24(7):455-60.
Bunevicius, A., Peceliuniene, J., Mickuviene, N., Valius, L., & Bunevicius, R. (2007). Screening for depression and anxiety disorders in primary care patients. Depression and Anxiety, 24(7), 455-60.
Bunevicius A, et al. Screening for Depression and Anxiety Disorders in Primary Care Patients. Depress Anxiety. 2007;24(7):455-60. PubMed PMID: 17117433.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for depression and anxiety disorders in primary care patients. AU - Bunevicius,Adomas, AU - Peceliuniene,Jurate, AU - Mickuviene,Narseta, AU - Valius,Leonas, AU - Bunevicius,Robertas, PY - 2006/11/23/pubmed PY - 2008/1/15/medline PY - 2006/11/23/entrez SP - 455 EP - 60 JF - Depression and anxiety JO - Depress Anxiety VL - 24 IS - 7 N2 - Mood and anxiety disorders are highly prevalent in primary health care. In this study we assessed performance of the Hospital Anxiety and Depression Scale (HADS) for screening of depression and anxiety disorders in a population of primary care patients. A total of 503 primary care patients consecutively admitted to the primary care medical center in Kaunas, Lithuania, completed the study. We found that the HADS subscale of depression (HADS-D) at a cutoff score of 6 or more showed the best performance screening for a major depressive episode diagnosed by means of the Mini International Neuropsychiatric Interview (MINI), with a sensitivity of 80%, specificity of 69%, positive predictive value of 80%, negative predictive value of 92%, and area under the receiver operating characteristic (ROC) curve of 0.75. Performance of the HADS-D against MINI diagnosis of dysthymia was weak. The HADS subscale of anxiety (HADS-A) at a cutoff score of 9 or more showed the best performance screening for MINI diagnosis of overall anxiety disorders, with a sensitivity of 77%, specificity of 75%, positive predictive value of 53%, negative predictive value of 90%, and area under the ROC curve of 0.76. These results suggest that in primary care patients HADS is an adequate screening instrument for the MINI diagnoses of major depressive episode, but not for dysthymia at a cutoff score of 6, and for anxiety disorders at a cutoff score of 9. SN - 1091-4269 UR - https://www.unboundmedicine.com/medline/citation/17117433/Screening_for_depression_and_anxiety_disorders_in_primary_care_patients_ L2 - https://doi.org/10.1002/da.20274 DB - PRIME DP - Unbound Medicine ER -