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S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in predementia syndromes and Alzheimer's disease.
Neurobiol Aging 2008; 29(3):478-80NA

Abstract

Recent epidemiological evidence showed that dietary fatty acids, antioxidants, and micronutrients appear to have a role in cognitive decline, and may permit a beneficial effect on the risk of dementia and predementia syndromes. We discussed in the present paper the issue of the suggested protective role of polyunsaturated fatty acids (PUFA) on Alzheimer's disease, mild cognitive impairment, and other predementia syndromes, supported by the findings of the Italian Longitudinal Study on Aging (ILSA) and other population-based studies. In particular, we discussed the possible metabolic link of plasma S-adenosylhomocysteine concentrations with PUFA erythrocyte composition in explaining this suggested protective role of fatty acids against dementia and predementia syndromes.

Authors+Show Affiliations

Department of Geriatrics, Center for Aging Brain, Memory Unit, University of Bari, Bari, Italy. geriat.dot@geriatria.uniba.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17125887

Citation

Panza, Francesco, et al. "S-adenosylhomocysteine and Polyunsaturated Fatty Acid Metabolism in Predementia Syndromes and Alzheimer's Disease." Neurobiology of Aging, vol. 29, no. 3, 2008, pp. 478-80.
Panza F, Capurso C, D'Introno A, et al. S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in predementia syndromes and Alzheimer's disease. Neurobiol Aging. 2008;29(3):478-80.
Panza, F., Capurso, C., D'Introno, A., Colacicco, A. M., Capurso, A., & Solfrizzi, V. (2008). S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in predementia syndromes and Alzheimer's disease. Neurobiology of Aging, 29(3), pp. 478-80.
Panza F, et al. S-adenosylhomocysteine and Polyunsaturated Fatty Acid Metabolism in Predementia Syndromes and Alzheimer's Disease. Neurobiol Aging. 2008;29(3):478-80. PubMed PMID: 17125887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in predementia syndromes and Alzheimer's disease. AU - Panza,Francesco, AU - Capurso,Cristiano, AU - D'Introno,Alessia, AU - Colacicco,Anna M, AU - Capurso,Antonio, AU - Solfrizzi,Vincenzo, Y1 - 2006/11/27/ PY - 2006/10/03/received PY - 2006/10/08/accepted PY - 2006/11/28/pubmed PY - 2008/3/28/medline PY - 2006/11/28/entrez SP - 478 EP - 80 JF - Neurobiology of aging JO - Neurobiol. Aging VL - 29 IS - 3 N2 - Recent epidemiological evidence showed that dietary fatty acids, antioxidants, and micronutrients appear to have a role in cognitive decline, and may permit a beneficial effect on the risk of dementia and predementia syndromes. We discussed in the present paper the issue of the suggested protective role of polyunsaturated fatty acids (PUFA) on Alzheimer's disease, mild cognitive impairment, and other predementia syndromes, supported by the findings of the Italian Longitudinal Study on Aging (ILSA) and other population-based studies. In particular, we discussed the possible metabolic link of plasma S-adenosylhomocysteine concentrations with PUFA erythrocyte composition in explaining this suggested protective role of fatty acids against dementia and predementia syndromes. SN - 1558-1497 UR - https://www.unboundmedicine.com/medline/citation/17125887/S_adenosylhomocysteine_and_polyunsaturated_fatty_acid_metabolism_in_predementia_syndromes_and_Alzheimer's_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0197-4580(06)00390-3 DB - PRIME DP - Unbound Medicine ER -