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Protective effect of Indigofera aspalathoides against CCl4-induced hepatic damage in rats.
J Herb Pharmacother. 2006; 6(1):49-54.JH

Abstract

The alcoholic extract of stem of Indigofera aspalathoides was evaluated for its antihepatotoxic activity against CCl(4)-induced hepatic damage in rats. The activity was evaluated by using biochemical parameters, such as serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total bilirubin and gama glutamate transpeptidase (GGTP). The histopathological changes of liver sample were compared with respective control. The extract showed remarkable hepatoprotective effect.

Authors+Show Affiliations

Rajkapoor B
Department of Pharmacology, Vinayaka Mission's College of Pharmacy, Yercaud Road, Salem 636 008, Tamilnadu, India. rajkapoorb@yahoo.co.in
Jayakar B
No affiliation info available
Kavimani S
No affiliation info available
Murugesh N
No affiliation info available

MeSH

Alanine TransaminaseAlkaline PhosphataseAnimalsAspartate AminotransferasesCarbon Tetrachloride PoisoningChemical and Drug Induced Liver InjuryDose-Response Relationship, DrugIndigoferaLiverPhytotherapyPlant ExtractsProtective AgentsRatsRats, WistarSerum Albumingamma-Glutamyltransferase

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17135160

Citation

Rajkapoor, B, et al. "Protective Effect of Indigofera Aspalathoides Against CCl4-induced Hepatic Damage in Rats." Journal of Herbal Pharmacotherapy, vol. 6, no. 1, 2006, pp. 49-54.
Rajkapoor B, Jayakar B, Kavimani S, et al. Protective effect of Indigofera aspalathoides against CCl4-induced hepatic damage in rats. J Herb Pharmacother. 2006;6(1):49-54.
Rajkapoor, B., Jayakar, B., Kavimani, S., & Murugesh, N. (2006). Protective effect of Indigofera aspalathoides against CCl4-induced hepatic damage in rats. Journal of Herbal Pharmacotherapy, 6(1), 49-54.
Rajkapoor B, et al. Protective Effect of Indigofera Aspalathoides Against CCl4-induced Hepatic Damage in Rats. J Herb Pharmacother. 2006;6(1):49-54. PubMed PMID: 17135160.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Protective effect of Indigofera aspalathoides against CCl4-induced hepatic damage in rats. AU - Rajkapoor,B, AU - Jayakar,B, AU - Kavimani,S, AU - Murugesh,N, PY - 2006/12/1/pubmed PY - 2007/2/28/medline PY - 2006/12/1/entrez SP - 49 EP - 54 JF - Journal of herbal pharmacotherapy JO - J Herb Pharmacother VL - 6 IS - 1 N2 - The alcoholic extract of stem of Indigofera aspalathoides was evaluated for its antihepatotoxic activity against CCl(4)-induced hepatic damage in rats. The activity was evaluated by using biochemical parameters, such as serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total bilirubin and gama glutamate transpeptidase (GGTP). The histopathological changes of liver sample were compared with respective control. The extract showed remarkable hepatoprotective effect. SN - 1522-8940 UR - https://www.unboundmedicine.com/medline/citation/17135160/Protective_effect_of_Indigofera_aspalathoides_against_CCl4_induced_hepatic_damage_in_rats_ L2 - https://medlineplus.gov/herbalmedicine.html DB - PRIME DP - Unbound Medicine ER -