Palladium-catalyzed sonogashira and hiyama reactions using phosphine-free hydrazone ligands.J Org Chem. 2006 Dec 08; 71(25):9499-502.JO
Abstract
Palladium/copper-catalyzed Sonogashira cross-coupling reaction of aryl halides with a variety of terminal alkynes under amine-free conditions in dimethylformamide (DMF) at 80 degrees C gave internal arylated alkynes using PdCl2(MeCN)2 with phosphine-free hydrazone 2a as a ligand and CuI as the cocatalyst in good yields. We also found PdCl2/hydrazone ligand 1d in PhMe at 80 degrees C was a phosphine-free efficient catalyst system for a Hiyama cross-coupling reaction of aryl bromides with aryl(trialkoxy)silanes in good yields.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
17137381
Citation
Mino, Takashi, et al. "Palladium-catalyzed Sonogashira and Hiyama Reactions Using Phosphine-free Hydrazone Ligands." The Journal of Organic Chemistry, vol. 71, no. 25, 2006, pp. 9499-502.
Mino T, Shirae Y, Saito T, et al. Palladium-catalyzed sonogashira and hiyama reactions using phosphine-free hydrazone ligands. J Org Chem. 2006;71(25):9499-502.
Mino, T., Shirae, Y., Saito, T., Sakamoto, M., & Fujita, T. (2006). Palladium-catalyzed sonogashira and hiyama reactions using phosphine-free hydrazone ligands. The Journal of Organic Chemistry, 71(25), 9499-502.
Mino T, et al. Palladium-catalyzed Sonogashira and Hiyama Reactions Using Phosphine-free Hydrazone Ligands. J Org Chem. 2006 Dec 8;71(25):9499-502. PubMed PMID: 17137381.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Palladium-catalyzed sonogashira and hiyama reactions using phosphine-free hydrazone ligands.
AU - Mino,Takashi,
AU - Shirae,Yoshiaki,
AU - Saito,Takeshi,
AU - Sakamoto,Masami,
AU - Fujita,Tsutomu,
PY - 2006/12/2/pubmed
PY - 2006/12/2/medline
PY - 2006/12/2/entrez
SP - 9499
EP - 502
JF - The Journal of organic chemistry
JO - J Org Chem
VL - 71
IS - 25
N2 - Palladium/copper-catalyzed Sonogashira cross-coupling reaction of aryl halides with a variety of terminal alkynes under amine-free conditions in dimethylformamide (DMF) at 80 degrees C gave internal arylated alkynes using PdCl2(MeCN)2 with phosphine-free hydrazone 2a as a ligand and CuI as the cocatalyst in good yields. We also found PdCl2/hydrazone ligand 1d in PhMe at 80 degrees C was a phosphine-free efficient catalyst system for a Hiyama cross-coupling reaction of aryl bromides with aryl(trialkoxy)silanes in good yields.
SN - 0022-3263
UR - https://www.unboundmedicine.com/medline/citation/17137381/Palladium_catalyzed_sonogashira_and_hiyama_reactions_using_phosphine_free_hydrazone_ligands_
L2 - https://doi.org/10.1021/jo061734i
DB - PRIME
DP - Unbound Medicine
ER -
