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[Favorable effects of decreasing lipids in patients with diabetes mellitus].
Dtsch Med Wochenschr. 2006 Dec; 131 Suppl 8:S252-4.DM

Abstract

Patients with diabetes mellitus are patients at high risk for cardiovascular events. There is only limited number of studies examining the effects of lipid lowering specifically in diabetics. The majority of evidence is derived from subgroup analyses of large intervention trials. Patients with diabetes mellitus benefit from a therapy with statins, independently from the starting LDL cholesterol concentrations. Furthermore, recent studies strongly suggest that for high risk patients such as diabetics regarding LDL "the lower is the better" The data for the benefits of fibrate therapy is not as robust as those available for statins. Therefore, at present no specific recommendation for treatment of diabetics with fibrates can be made.

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Authors+Show Affiliations

Gouni-Berthold I
Klinik II und Poliklinik für Innere Medizin der Universität zu Köln, Köln, Germany. ioanna.berthold@uni-koeln.de
Krone W
No affiliation info available

MeSH

Anticholesteremic AgentsCardiovascular DiseasesCholesterol, HDLCholesterol, LDLClofibric AcidDiabetes ComplicationsDiabetes Mellitus, Type 2HumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasHypolipidemic AgentsRisk FactorsTreatment Outcome

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

17139581

Citation

Gouni-Berthold, I, and W Krone. "[Favorable Effects of Decreasing Lipids in Patients With Diabetes Mellitus]." Deutsche Medizinische Wochenschrift (1946), vol. 131 Suppl 8, 2006, pp. S252-4.
Gouni-Berthold I, Krone W. [Favorable effects of decreasing lipids in patients with diabetes mellitus]. Dtsch Med Wochenschr. 2006;131 Suppl 8:S252-4.
Gouni-Berthold, I., & Krone, W. (2006). [Favorable effects of decreasing lipids in patients with diabetes mellitus]. Deutsche Medizinische Wochenschrift (1946), 131 Suppl 8, S252-4.
Gouni-Berthold I, Krone W. [Favorable Effects of Decreasing Lipids in Patients With Diabetes Mellitus]. Dtsch Med Wochenschr. 2006;131 Suppl 8:S252-4. PubMed PMID: 17139581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Favorable effects of decreasing lipids in patients with diabetes mellitus]. AU - Gouni-Berthold,I, AU - Krone,W, PY - 2006/12/2/pubmed PY - 2007/8/24/medline PY - 2006/12/2/entrez SP - S252 EP - 4 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch Med Wochenschr VL - 131 Suppl 8 N2 - Patients with diabetes mellitus are patients at high risk for cardiovascular events. There is only limited number of studies examining the effects of lipid lowering specifically in diabetics. The majority of evidence is derived from subgroup analyses of large intervention trials. Patients with diabetes mellitus benefit from a therapy with statins, independently from the starting LDL cholesterol concentrations. Furthermore, recent studies strongly suggest that for high risk patients such as diabetics regarding LDL "the lower is the better" The data for the benefits of fibrate therapy is not as robust as those available for statins. Therefore, at present no specific recommendation for treatment of diabetics with fibrates can be made. SN - 1439-4413 UR - https://www.unboundmedicine.com/medline/citation/17139581/[Favorable_effects_of_decreasing_lipids_in_patients_with_diabetes_mellitus]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-956284 DB - PRIME DP - Unbound Medicine ER -