Tags

Type your tag names separated by a space and hit enter

[Chemical constituents from roots of Platycodon grandiflorum].
Zhongguo Zhong Yao Za Zhi. 2006 Sep; 31(18):1506-9.ZZ

Abstract

OBJECTIVE

To study the chemical constituents from roots of Platycodon grandiflorum.

METHOD

Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data.

RESULT

Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).

CONCLUSION

Compounds 1,3 and 5 were isolated from this plant for the first time.

Authors+Show Affiliations

Li LJ
Department of Chinese Medicine Science and Engineering, Zhejiang University, Hangzhou 310028, China.
Liu ZH
No affiliation info available
Chen Y
No affiliation info available
Tian JK
No affiliation info available

MeSH

FlavonesLactonesOleanolic AcidPlant ExtractsPlant RootsPlants, MedicinalPlatycodonSaponins

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

17144467

Citation

Li, Ling-Jun, et al. "[Chemical Constituents From Roots of Platycodon Grandiflorum]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 31, no. 18, 2006, pp. 1506-9.
Li LJ, Liu ZH, Chen Y, et al. [Chemical constituents from roots of Platycodon grandiflorum]. Zhongguo Zhong Yao Za Zhi. 2006;31(18):1506-9.
Li, L. J., Liu, Z. H., Chen, Y., & Tian, J. K. (2006). [Chemical constituents from roots of Platycodon grandiflorum]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 31(18), 1506-9.
Li LJ, et al. [Chemical Constituents From Roots of Platycodon Grandiflorum]. Zhongguo Zhong Yao Za Zhi. 2006;31(18):1506-9. PubMed PMID: 17144467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Chemical constituents from roots of Platycodon grandiflorum]. AU - Li,Ling-Jun, AU - Liu,Zhen-Hua, AU - Chen,Yun, AU - Tian,Jing-Kui, PY - 2006/12/6/pubmed PY - 2007/10/20/medline PY - 2006/12/6/entrez SP - 1506 EP - 9 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 31 IS - 18 N2 - OBJECTIVE: To study the chemical constituents from roots of Platycodon grandiflorum. METHOD: Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data. RESULT: Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8). CONCLUSION: Compounds 1,3 and 5 were isolated from this plant for the first time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/17144467/[Chemical_constituents_from_roots_of_Platycodon_grandiflorum]_ DB - PRIME DP - Unbound Medicine ER -