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[The morphogenesis and spatial organization of human pineal gland concretions in Alzheimer's disease, schizophrenia, and alcoholism].
Arkh Patol 2006 Sep-Oct; 68(5):20-2AP

Abstract

X-ray microtomography using a wavelength of 0.7 A was used to detect elevated calcium concentration areas that integrate all types of human epiphyseal concretions. They consisted of both concretions and extracellular calcium, which could not be attributed to any particular tissue. There were no concretions outside of these zones. The center of concretion formation was found to be a single source that may be an individual pinealocyte. Comparison of postmortem human epiphyses in normalcy (natural aging), in chronic alcoholism, Alzheimer's disease, and schizophrenia revealed that there were differences in both the number of concretions and their formation topology. In normalcy, the field of elevated calcium concentration was continuous whereas in patients with the study mental diseases, it was divided into separate areas. There is evidence that in mental diseases, the amount of acervulus and its density decrease, which may a marker of the development of these diseases.

Pub Type(s)

Journal Article

Language

rus

PubMed ID

17144525

Citation

Fokin, E I., et al. "[The Morphogenesis and Spatial Organization of Human Pineal Gland Concretions in Alzheimer's Disease, Schizophrenia, and Alcoholism]." Arkhiv Patologii, vol. 68, no. 5, 2006, pp. 20-2.
Fokin EI, Savel'ev SV, Gulimova VI, et al. [The morphogenesis and spatial organization of human pineal gland concretions in Alzheimer's disease, schizophrenia, and alcoholism]. Arkh Patol. 2006;68(5):20-2.
Fokin, E. I., Savel'ev, S. V., Gulimova, V. I., Asadchikov, E. V., Senin, R. A., & Buzmakov, A. V. (2006). [The morphogenesis and spatial organization of human pineal gland concretions in Alzheimer's disease, schizophrenia, and alcoholism]. Arkhiv Patologii, 68(5), pp. 20-2.
Fokin EI, et al. [The Morphogenesis and Spatial Organization of Human Pineal Gland Concretions in Alzheimer's Disease, Schizophrenia, and Alcoholism]. Arkh Patol. 2006;68(5):20-2. PubMed PMID: 17144525.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The morphogenesis and spatial organization of human pineal gland concretions in Alzheimer's disease, schizophrenia, and alcoholism]. AU - Fokin,E I, AU - Savel'ev,S V, AU - Gulimova,V I, AU - Asadchikov,E V, AU - Senin,R A, AU - Buzmakov,A V, PY - 2006/12/6/pubmed PY - 2007/1/4/medline PY - 2006/12/6/entrez SP - 20 EP - 2 JF - Arkhiv patologii JO - Arkh. Patol. VL - 68 IS - 5 N2 - X-ray microtomography using a wavelength of 0.7 A was used to detect elevated calcium concentration areas that integrate all types of human epiphyseal concretions. They consisted of both concretions and extracellular calcium, which could not be attributed to any particular tissue. There were no concretions outside of these zones. The center of concretion formation was found to be a single source that may be an individual pinealocyte. Comparison of postmortem human epiphyses in normalcy (natural aging), in chronic alcoholism, Alzheimer's disease, and schizophrenia revealed that there were differences in both the number of concretions and their formation topology. In normalcy, the field of elevated calcium concentration was continuous whereas in patients with the study mental diseases, it was divided into separate areas. There is evidence that in mental diseases, the amount of acervulus and its density decrease, which may a marker of the development of these diseases. SN - 0004-1955 UR - https://www.unboundmedicine.com/medline/citation/17144525/[The_morphogenesis_and_spatial_organization_of_human_pineal_gland_concretions_in_Alzheimer's_disease,_schizophrenia,_and_alcoholism] L2 - http://www.diseaseinfosearch.org/result/6442 DB - PRIME DP - Unbound Medicine ER -