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[The cytofluorometric opinion of expression of adhesion molecules CD11a and CD54 on lymphocytes T and B in children's hypertrophied adenoids, which are sick on the otitis media with effusion].
Otolaryngol Pol. 2006; 60(4):565-70.OP

Abstract

INTRODUCTION

Otitis media with effusion (WZU) is highly prevalent among young children. The hypertrophied adenoid favorables to development (WZU). The pharyngeal tonsil delivers the essential lymphocytes for developed immunological answer. The migrations of lymphocytes to pharyngeal tonsil and to places inflammatory proceed with part of adhesive molecules (CD11a, CD54) presented on lymphocytes. The aim of this study was examination the percentage of the lymphocytes CD4+, CD8+ and lymphocytes B with expression of adhesion molecules ICAM-1 (CD54) and LFA-1 (CD11a). We examined their expression in hypertrophied adenoid by children with otitis media with effusion.

RESULTS

In investigations was showed statistically significant decrease of percentage of lymphocytes CD4+CD11a+ and CD8+CD11a+ and increase of percentage of lymphocytes CD19+CD54+ in otitis media with effusion in comparison to group with hypertrophied adenoid.

CONCLUSIONS

Molecule adhesive ICAM-1 and LFA-1 fulfills important part in many immunological processes proceed to pharyngeal tonsil. The considerably lower percentage of lymphocytes T CD4+ and CD8+ with expression LFA-1 in hypertrophied adenoids is possibly of causes of incorrect their immunological answer, and the same factor favourables to prolonging the otitis media with effusion at children.

Authors+Show Affiliations

Ratomski K
Zakład Laboratoryjnej Diagnostyki Pediatrycznej AM w Białymstoku. zldpam@poczta.fm
Wysocka J
No affiliation info available
Skotnicka B
No affiliation info available
Zelazowska-Rutkowska B
No affiliation info available
Hassmann-Poznańska E
No affiliation info available

MeSH

AdenoidectomyAdenoidsAdolescentB-LymphocytesCD11a AntigenChildChild, PreschoolFemaleFlow CytometryHumansHypertrophyIntercellular Adhesion Molecule-1MaleOtitis Media with EffusionT-Lymphocytes

Pub Type(s)

Journal Article

Language

pol

PubMed ID

17152810

Citation

Ratomski, Karol, et al. "[The Cytofluorometric Opinion of Expression of Adhesion Molecules CD11a and CD54 On Lymphocytes T and B in Children's Hypertrophied Adenoids, Which Are Sick On the Otitis Media With Effusion]." Otolaryngologia Polska = the Polish Otolaryngology, vol. 60, no. 4, 2006, pp. 565-70.
Ratomski K, Wysocka J, Skotnicka B, et al. [The cytofluorometric opinion of expression of adhesion molecules CD11a and CD54 on lymphocytes T and B in children's hypertrophied adenoids, which are sick on the otitis media with effusion]. Otolaryngol Pol. 2006;60(4):565-70.
Ratomski, K., Wysocka, J., Skotnicka, B., Zelazowska-Rutkowska, B., & Hassmann-Poznańska, E. (2006). [The cytofluorometric opinion of expression of adhesion molecules CD11a and CD54 on lymphocytes T and B in children's hypertrophied adenoids, which are sick on the otitis media with effusion]. Otolaryngologia Polska = the Polish Otolaryngology, 60(4), 565-70.
Ratomski K, et al. [The Cytofluorometric Opinion of Expression of Adhesion Molecules CD11a and CD54 On Lymphocytes T and B in Children's Hypertrophied Adenoids, Which Are Sick On the Otitis Media With Effusion]. Otolaryngol Pol. 2006;60(4):565-70. PubMed PMID: 17152810.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The cytofluorometric opinion of expression of adhesion molecules CD11a and CD54 on lymphocytes T and B in children's hypertrophied adenoids, which are sick on the otitis media with effusion]. AU - Ratomski,Karol, AU - Wysocka,Jolanta, AU - Skotnicka,Bozena, AU - Zelazowska-Rutkowska,Beata, AU - Hassmann-Poznańska,Elzbieta, PY - 2006/12/13/pubmed PY - 2007/1/24/medline PY - 2006/12/13/entrez SP - 565 EP - 70 JF - Otolaryngologia polska = The Polish otolaryngology JO - Otolaryngol Pol VL - 60 IS - 4 N2 - INTRODUCTION: Otitis media with effusion (WZU) is highly prevalent among young children. The hypertrophied adenoid favorables to development (WZU). The pharyngeal tonsil delivers the essential lymphocytes for developed immunological answer. The migrations of lymphocytes to pharyngeal tonsil and to places inflammatory proceed with part of adhesive molecules (CD11a, CD54) presented on lymphocytes. The aim of this study was examination the percentage of the lymphocytes CD4+, CD8+ and lymphocytes B with expression of adhesion molecules ICAM-1 (CD54) and LFA-1 (CD11a). We examined their expression in hypertrophied adenoid by children with otitis media with effusion. RESULTS: In investigations was showed statistically significant decrease of percentage of lymphocytes CD4+CD11a+ and CD8+CD11a+ and increase of percentage of lymphocytes CD19+CD54+ in otitis media with effusion in comparison to group with hypertrophied adenoid. CONCLUSIONS: Molecule adhesive ICAM-1 and LFA-1 fulfills important part in many immunological processes proceed to pharyngeal tonsil. The considerably lower percentage of lymphocytes T CD4+ and CD8+ with expression LFA-1 in hypertrophied adenoids is possibly of causes of incorrect their immunological answer, and the same factor favourables to prolonging the otitis media with effusion at children. SN - 0030-6657 UR - https://www.unboundmedicine.com/medline/citation/17152810/[The_cytofluorometric_opinion_of_expression_of_adhesion_molecules_CD11a_and_CD54_on_lymphocytes_T_and_B_in_children's_hypertrophied_adenoids_which_are_sick_on_the_otitis_media_with_effusion]_ L2 - https://medlineplus.gov/adenoids.html DB - PRIME DP - Unbound Medicine ER -