Tags

Type your tag names separated by a space and hit enter

Erythema multiforme due to Mycoplasma pneumoniae infection in two children.
Pediatr Dermatol. 2006 Nov-Dec; 23(6):546-55.PD

Abstract

Mycoplasma pneumoniae is an important and highly relevant cause of bullous erythema multiforme, isolated mucositis, and Stevens-Johnson syndrome in children. In this article, we present two children with respiratory Mycoplasma pneumoniae infection and associated cutaneous findings within the spectrum of erythema multiforme. We review the literature associating these three entities with Mycoplasma pneumoniae infection and discuss controversies regarding the classification of erythema multiforme, as well as update reported infectious causes of the bullous form. Many understand the erythema multiforme spectrum to include bullous erythema multiforme, mucositis, and Stevens-Johnson syndrome in the order of increasing severity. We feel that this relationship should be reconsidered to help better understand the prognosis and outcomes. It is our opinion that bullous erythema multiforme is a separate, yet related condition that can occur in the context of Mycoplasma pneumoniae infection. With many similarities to mucositis and Stevens-Johnson syndrome, bullous erythema multiforme can be considered part of a spectrum of disease that includes Stevens-Johnson syndrome. Unlike mucositis and Stevens-Johnson syndrome, bullous erythema multiforme caused by Mycoplasma pneumoniae infection has low morbidity for the child. Mycoplasma pneumoniae-associated mucositis and Stevens-Johnson syndrome seem to occur along a spectrum with separate prognosis and potential pathogenesis compared with bullous erythema multiforme. Making the distinction between these conditions is valuable for predicting the child's prognosis. Patients who develop symptoms consistent with these conditions should be appropriately evaluated for Mycoplasma pneumoniae infection and closely monitored.

Authors+Show Affiliations

Department of Dermatology, Harvard Medical School, Boston, Massachasetts, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

17155996

Citation

Schalock, Peter C., et al. "Erythema Multiforme Due to Mycoplasma Pneumoniae Infection in Two Children." Pediatric Dermatology, vol. 23, no. 6, 2006, pp. 546-55.
Schalock PC, Dinulos JG, Pace N, et al. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatr Dermatol. 2006;23(6):546-55.
Schalock, P. C., Dinulos, J. G., Pace, N., Schwarzenberger, K., & Wenger, J. K. (2006). Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Pediatric Dermatology, 23(6), 546-55.
Schalock PC, et al. Erythema Multiforme Due to Mycoplasma Pneumoniae Infection in Two Children. Pediatr Dermatol. 2006 Nov-Dec;23(6):546-55. PubMed PMID: 17155996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Erythema multiforme due to Mycoplasma pneumoniae infection in two children. AU - Schalock,Peter C, AU - Dinulos,James G H, AU - Pace,Nicole, AU - Schwarzenberger,Kathryn, AU - Wenger,Jodi K, PY - 2006/12/13/pubmed PY - 2007/10/5/medline PY - 2006/12/13/entrez SP - 546 EP - 55 JF - Pediatric dermatology JO - Pediatr Dermatol VL - 23 IS - 6 N2 - Mycoplasma pneumoniae is an important and highly relevant cause of bullous erythema multiforme, isolated mucositis, and Stevens-Johnson syndrome in children. In this article, we present two children with respiratory Mycoplasma pneumoniae infection and associated cutaneous findings within the spectrum of erythema multiforme. We review the literature associating these three entities with Mycoplasma pneumoniae infection and discuss controversies regarding the classification of erythema multiforme, as well as update reported infectious causes of the bullous form. Many understand the erythema multiforme spectrum to include bullous erythema multiforme, mucositis, and Stevens-Johnson syndrome in the order of increasing severity. We feel that this relationship should be reconsidered to help better understand the prognosis and outcomes. It is our opinion that bullous erythema multiforme is a separate, yet related condition that can occur in the context of Mycoplasma pneumoniae infection. With many similarities to mucositis and Stevens-Johnson syndrome, bullous erythema multiforme can be considered part of a spectrum of disease that includes Stevens-Johnson syndrome. Unlike mucositis and Stevens-Johnson syndrome, bullous erythema multiforme caused by Mycoplasma pneumoniae infection has low morbidity for the child. Mycoplasma pneumoniae-associated mucositis and Stevens-Johnson syndrome seem to occur along a spectrum with separate prognosis and potential pathogenesis compared with bullous erythema multiforme. Making the distinction between these conditions is valuable for predicting the child's prognosis. Patients who develop symptoms consistent with these conditions should be appropriately evaluated for Mycoplasma pneumoniae infection and closely monitored. SN - 0736-8046 UR - https://www.unboundmedicine.com/medline/citation/17155996/Erythema_multiforme_due_to_Mycoplasma_pneumoniae_infection_in_two_children_ L2 - https://doi.org/10.1111/j.1525-1470.2006.00307.x DB - PRIME DP - Unbound Medicine ER -