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Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium.
Eye (Lond). 2008 Mar; 22(3):420-4.E

Abstract

AIM

To compare the efficacy and complications of conjunctival limbal autograft (CLAU) and amniotic membrane transplantation (AMT) vsintraoperative mitomycin C (MMC) and AMT for treatment of recurrent pterygium.

METHODS

Forty eyes of 40 patients with recurrent pterygium underwent CLAU and AMT (20 eyes) or intraoperative MMC (0.02%, 3 min) and AMT (20 eyes). Three eyes (15%) had symblepharon before surgery in each group. Recurrence was compared in each group by using chi(2) test.

RESULTS

No major postoperative complications occurred during 6-19 months of follow-up. In CLAU/AMT group, no pterygium recurrence was observed. Recurrence occurred in four eyes (20%) in MMC/AMT group after 3 and 4 months (P-value=0.035, chi(2) test). No recurrence of pterygium or symblepharon was seen in six eyes with recurrent pterygium and symblepharon (three eyes in each group).

CONCLUSION

CLAU with AMT seems to be more effective than intraoperative MMC with AMT for treatment of recurrent pterygium.

Authors+Show Affiliations

Department of Ophthalmology, Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Science, Tehran, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17159974

Citation

Fallah, M R., et al. "Transplantation of Conjunctival Limbal Autograft and Amniotic Membrane Vs Mitomycin C and Amniotic Membrane in Treatment of Recurrent Pterygium." Eye (London, England), vol. 22, no. 3, 2008, pp. 420-4.
Fallah MR, Golabdar MR, Amozadeh J, et al. Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium. Eye (Lond). 2008;22(3):420-4.
Fallah, M. R., Golabdar, M. R., Amozadeh, J., Zare, M. A., Moghimi, S., & Fakhraee, G. (2008). Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium. Eye (London, England), 22(3), 420-4.
Fallah MR, et al. Transplantation of Conjunctival Limbal Autograft and Amniotic Membrane Vs Mitomycin C and Amniotic Membrane in Treatment of Recurrent Pterygium. Eye (Lond). 2008;22(3):420-4. PubMed PMID: 17159974.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Transplantation of conjunctival limbal autograft and amniotic membrane vs mitomycin C and amniotic membrane in treatment of recurrent pterygium. AU - Fallah,M R, AU - Golabdar,M R, AU - Amozadeh,J, AU - Zare,M A, AU - Moghimi,S, AU - Fakhraee,G, Y1 - 2006/12/08/ PY - 2006/12/13/pubmed PY - 2008/9/11/medline PY - 2006/12/13/entrez SP - 420 EP - 4 JF - Eye (London, England) JO - Eye (Lond) VL - 22 IS - 3 N2 - AIM: To compare the efficacy and complications of conjunctival limbal autograft (CLAU) and amniotic membrane transplantation (AMT) vsintraoperative mitomycin C (MMC) and AMT for treatment of recurrent pterygium. METHODS: Forty eyes of 40 patients with recurrent pterygium underwent CLAU and AMT (20 eyes) or intraoperative MMC (0.02%, 3 min) and AMT (20 eyes). Three eyes (15%) had symblepharon before surgery in each group. Recurrence was compared in each group by using chi(2) test. RESULTS: No major postoperative complications occurred during 6-19 months of follow-up. In CLAU/AMT group, no pterygium recurrence was observed. Recurrence occurred in four eyes (20%) in MMC/AMT group after 3 and 4 months (P-value=0.035, chi(2) test). No recurrence of pterygium or symblepharon was seen in six eyes with recurrent pterygium and symblepharon (three eyes in each group). CONCLUSION: CLAU with AMT seems to be more effective than intraoperative MMC with AMT for treatment of recurrent pterygium. SN - 0950-222X UR - https://www.unboundmedicine.com/medline/citation/17159974/Transplantation_of_conjunctival_limbal_autograft_and_amniotic_membrane_vs_mitomycin_C_and_amniotic_membrane_in_treatment_of_recurrent_pterygium_ L2 - https://doi.org/10.1038/sj.eye.6702657 DB - PRIME DP - Unbound Medicine ER -