Tags

Type your tag names separated by a space and hit enter

[Studies on diterpenoids from Andrographis paniculata].
Zhongguo Zhong Yao Za Zhi. 2006 Oct; 31(19):1594-7.ZZ

Abstract

OBJECTIVE

To study the diterpenoids in the 85% ethanol extract of the aerial parts of Andrographis paniculata.

METHOD

Fourteen diterpenoids from the 85% EtOH extract were isolated by the silica gel, Sephadex LH-20, ODS column chromatography and HPLC, and their structures were identified by the spectal analyses and chemical evidences.

RESULT

The 14 compounds were obtained and identified as neoandrographolide (1), 3, 14-di-deoxyandrographolide (2), andrographolide (3), 14-deoxy-11, 12-didehydroandrographolide (4), 19-hydroxy-8 (17), 13-labdadien-15, 16-olide (5), 14-deoxy-andrographolide (6), 3-oxo-14-deoxy-andrographolide (7), isoandrographolide, (8), bisandrographolide (9, 10, 11), deoxyandrographiside (12), 14-deoxy-11, 12-didehydroandrographiside (13), andrographiside (14), respectively.

CONCLUSION

Compound 7 was a new natural product, and compound 5 was obtained for the first time from the Andrographis species.

Authors+Show Affiliations

Chen LX
Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China.
Qu GX
No affiliation info available
Qiu F
No affiliation info available

MeSH

AndrographisDiterpenesGlucosidesMolecular StructurePlant Components, AerialPlants, MedicinalTetrahydronaphthalenes

Pub Type(s)

Journal Article

Language

chi

PubMed ID

17165582

Citation

Chen, Li-Xia, et al. "[Studies On Diterpenoids From Andrographis Paniculata]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 31, no. 19, 2006, pp. 1594-7.
Chen LX, Qu GX, Qiu F. [Studies on diterpenoids from Andrographis paniculata]. Zhongguo Zhong Yao Za Zhi. 2006;31(19):1594-7.
Chen, L. X., Qu, G. X., & Qiu, F. (2006). [Studies on diterpenoids from Andrographis paniculata]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 31(19), 1594-7.
Chen LX, Qu GX, Qiu F. [Studies On Diterpenoids From Andrographis Paniculata]. Zhongguo Zhong Yao Za Zhi. 2006;31(19):1594-7. PubMed PMID: 17165582.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Studies on diterpenoids from Andrographis paniculata]. AU - Chen,Li-Xia, AU - Qu,Ge-Xia, AU - Qiu,Feng, PY - 2006/12/15/pubmed PY - 2007/11/2/medline PY - 2006/12/15/entrez SP - 1594 EP - 7 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 31 IS - 19 N2 - OBJECTIVE: To study the diterpenoids in the 85% ethanol extract of the aerial parts of Andrographis paniculata. METHOD: Fourteen diterpenoids from the 85% EtOH extract were isolated by the silica gel, Sephadex LH-20, ODS column chromatography and HPLC, and their structures were identified by the spectal analyses and chemical evidences. RESULT: The 14 compounds were obtained and identified as neoandrographolide (1), 3, 14-di-deoxyandrographolide (2), andrographolide (3), 14-deoxy-11, 12-didehydroandrographolide (4), 19-hydroxy-8 (17), 13-labdadien-15, 16-olide (5), 14-deoxy-andrographolide (6), 3-oxo-14-deoxy-andrographolide (7), isoandrographolide, (8), bisandrographolide (9, 10, 11), deoxyandrographiside (12), 14-deoxy-11, 12-didehydroandrographiside (13), andrographiside (14), respectively. CONCLUSION: Compound 7 was a new natural product, and compound 5 was obtained for the first time from the Andrographis species. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/17165582/[Studies_on_diterpenoids_from_Andrographis_paniculata]_ L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:17165582 DB - PRIME DP - Unbound Medicine ER -