Tags

Type your tag names separated by a space and hit enter

Municipal mortality due to thyroid cancer in Spain.
BMC Public Health 2006; 6:302BP

Abstract

BACKGROUND

Thyroid cancer is a tumor with a low but growing incidence in Spain. This study sought to depict its spatial municipal mortality pattern, using the classic model proposed by Besag, York and Mollié.

METHODS

It was possible to compile and ascertain the posterior distribution of relative risk on the basis of a single Bayesian spatial model covering all of Spain's 8077 municipal areas. Maps were plotted depicting standardized mortality ratios, smoothed relative risk (RR) estimates, and the posterior probability that RR > 1.

RESULTS

From 1989 to 1998 a total of 2,538 thyroid cancer deaths were registered in 1,041 municipalities. The highest relative risks were mostly situated in the Canary Islands, the province of Lugo, the east of La Coruña (Corunna) and western areas of Asturias and Orense.

CONCLUSION

The observed mortality pattern coincides with areas in Spain where goiter has been declared endemic. The higher frequency in these same areas of undifferentiated, more aggressive carcinomas could be reflected in the mortality figures. Other unknown genetic or environmental factors could also play a role in the etiology of this tumor.

Authors+Show Affiliations

Cancer and Environmental Epidemiology Area, National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain. vicarvajal@isciii.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17173668

Citation

Lope, Virginia, et al. "Municipal Mortality Due to Thyroid Cancer in Spain." BMC Public Health, vol. 6, 2006, p. 302.
Lope V, Pollán M, Pérez-Gómez B, et al. Municipal mortality due to thyroid cancer in Spain. BMC Public Health. 2006;6:302.
Lope, V., Pollán, M., Pérez-Gómez, B., Aragonés, N., Ramis, R., Gómez-Barroso, D., & López-Abente, G. (2006). Municipal mortality due to thyroid cancer in Spain. BMC Public Health, 6, p. 302.
Lope V, et al. Municipal Mortality Due to Thyroid Cancer in Spain. BMC Public Health. 2006 Dec 15;6:302. PubMed PMID: 17173668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Municipal mortality due to thyroid cancer in Spain. AU - Lope,Virginia, AU - Pollán,Marina, AU - Pérez-Gómez,Beatriz, AU - Aragonés,Nuria, AU - Ramis,Rebeca, AU - Gómez-Barroso,Diana, AU - López-Abente,Gonzalo, Y1 - 2006/12/15/ PY - 2006/07/04/received PY - 2006/12/15/accepted PY - 2006/12/19/pubmed PY - 2007/3/6/medline PY - 2006/12/19/entrez SP - 302 EP - 302 JF - BMC public health JO - BMC Public Health VL - 6 N2 - BACKGROUND: Thyroid cancer is a tumor with a low but growing incidence in Spain. This study sought to depict its spatial municipal mortality pattern, using the classic model proposed by Besag, York and Mollié. METHODS: It was possible to compile and ascertain the posterior distribution of relative risk on the basis of a single Bayesian spatial model covering all of Spain's 8077 municipal areas. Maps were plotted depicting standardized mortality ratios, smoothed relative risk (RR) estimates, and the posterior probability that RR > 1. RESULTS: From 1989 to 1998 a total of 2,538 thyroid cancer deaths were registered in 1,041 municipalities. The highest relative risks were mostly situated in the Canary Islands, the province of Lugo, the east of La Coruña (Corunna) and western areas of Asturias and Orense. CONCLUSION: The observed mortality pattern coincides with areas in Spain where goiter has been declared endemic. The higher frequency in these same areas of undifferentiated, more aggressive carcinomas could be reflected in the mortality figures. Other unknown genetic or environmental factors could also play a role in the etiology of this tumor. SN - 1471-2458 UR - https://www.unboundmedicine.com/medline/citation/17173668/Municipal_mortality_due_to_thyroid_cancer_in_Spain_ L2 - https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-6-302 DB - PRIME DP - Unbound Medicine ER -