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Alcohol consumption and risk of cataract extraction: a prospective cohort study of women.
Ophthalmology 2007; 114(4):680-5O

Abstract

PURPOSE

To investigate the association between alcohol consumption and the risk of cataract extraction.

DESIGN

Population-based prospective cohort study.

PARTICIPANTS

A total of 34,713 women participating in the Swedish Mammography Cohort, age 49 to 83 years, completed in 1997 a self-administered questionnaire about alcohol, smoking, and other lifestyle factors.

METHODS

The women were followed from September 1997 through September 2004. The cohort was matched with registers of cataract extraction from the study area.

MAIN OUTCOME MEASURES

Incident surgical extraction of age-related cataract.

RESULTS

During 84 months of follow-up, we found 3587 incident cases of age-related cataract extraction. Compared with never drinkers, the relative risk of cataract extraction among current drinkers was 1.11 (95% confidence interval [CI] 1.02-1.21) after adjustment for age and other potential risk factors. In multivariate analysis, an increment of 13 g alcohol intake per day (corresponding to 1 drink = 330 ml of beer, 150 ml of wine, or 45 ml of liquor) was associated with a 7% increased risk of cataract extraction (relative risk, 1.07; 95% CI 1.02-1.12). Mean age at cataract extraction among nonsmoking women who used alcohol was 75 years, compared with 77.6 years among never drinkers.

CONCLUSIONS

These prospective data suggest that daily use of >/=1 alcoholic drinks was associated with a modest increase of risk for cataract extraction. The risk increased with increasing alcohol consumption.

Authors+Show Affiliations

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. birgitta.ejdervik.lindblad@swipnet.seNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17173974

Citation

Lindblad, Birgitta Ejdervik, et al. "Alcohol Consumption and Risk of Cataract Extraction: a Prospective Cohort Study of Women." Ophthalmology, vol. 114, no. 4, 2007, pp. 680-5.
Lindblad BE, Håkansson N, Philipson B, et al. Alcohol consumption and risk of cataract extraction: a prospective cohort study of women. Ophthalmology. 2007;114(4):680-5.
Lindblad, B. E., Håkansson, N., Philipson, B., & Wolk, A. (2007). Alcohol consumption and risk of cataract extraction: a prospective cohort study of women. Ophthalmology, 114(4), pp. 680-5.
Lindblad BE, et al. Alcohol Consumption and Risk of Cataract Extraction: a Prospective Cohort Study of Women. Ophthalmology. 2007;114(4):680-5. PubMed PMID: 17173974.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and risk of cataract extraction: a prospective cohort study of women. AU - Lindblad,Birgitta Ejdervik, AU - Håkansson,Niclas, AU - Philipson,Bo, AU - Wolk,Alicja, Y1 - 2006/12/14/ PY - 2006/02/14/received PY - 2006/07/10/revised PY - 2006/07/11/accepted PY - 2006/12/19/pubmed PY - 2007/4/14/medline PY - 2006/12/19/entrez SP - 680 EP - 5 JF - Ophthalmology JO - Ophthalmology VL - 114 IS - 4 N2 - PURPOSE: To investigate the association between alcohol consumption and the risk of cataract extraction. DESIGN: Population-based prospective cohort study. PARTICIPANTS: A total of 34,713 women participating in the Swedish Mammography Cohort, age 49 to 83 years, completed in 1997 a self-administered questionnaire about alcohol, smoking, and other lifestyle factors. METHODS: The women were followed from September 1997 through September 2004. The cohort was matched with registers of cataract extraction from the study area. MAIN OUTCOME MEASURES: Incident surgical extraction of age-related cataract. RESULTS: During 84 months of follow-up, we found 3587 incident cases of age-related cataract extraction. Compared with never drinkers, the relative risk of cataract extraction among current drinkers was 1.11 (95% confidence interval [CI] 1.02-1.21) after adjustment for age and other potential risk factors. In multivariate analysis, an increment of 13 g alcohol intake per day (corresponding to 1 drink = 330 ml of beer, 150 ml of wine, or 45 ml of liquor) was associated with a 7% increased risk of cataract extraction (relative risk, 1.07; 95% CI 1.02-1.12). Mean age at cataract extraction among nonsmoking women who used alcohol was 75 years, compared with 77.6 years among never drinkers. CONCLUSIONS: These prospective data suggest that daily use of >/=1 alcoholic drinks was associated with a modest increase of risk for cataract extraction. The risk increased with increasing alcohol consumption. SN - 1549-4713 UR - https://www.unboundmedicine.com/medline/citation/17173974/Alcohol_consumption_and_risk_of_cataract_extraction:_a_prospective_cohort_study_of_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(06)01176-6 DB - PRIME DP - Unbound Medicine ER -