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Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample.
Nutr Metab Cardiovasc Dis. 2007 Jan; 17(1):41-9.NM

Abstract

BACKGROUND AND AIM

The ankle-brachial index (ABI) is being used increasingly to diagnose peripheral arterial disease (PAD) that predicts cardiovascular morbidity and mortality. The aim of this study is to determine the prevalence of PAD and associated risk factors in a Spanish random population sample of age > or =40.

METHODS AND RESULTS

PAD is defined as an ABI<0.9 in either leg. 784 participants of age > or =40 were randomly selected in a Spanish province. 55.4% of them were female. The prevalence of PAD in this sample was 10.5% (95% confidence interval (CI) 8.4-12.8); 9.7% in females and 11.4% in males. In logistic regression analyses, adjusted for age and gender, smoking per 10 pack-years (odds ratio (OR) 1.40, 95% CI 1.23-1.58), hypertension (OR 1.85, 95% CI 1.05-3.28), hypercholesterolemia (OR 1.76, 95% CI 1.04-2.98), and diabetes (OR 1.80, 95% CI 1.04-3.11) were positively associated with prevalent PAD. More than 91% of persons with PAD had one or more cardiovascular disease risk factors.

CONCLUSIONS

We conclude that in our study hypertension, hypercholesterolemia, diabetes mellitus and smoking are associated with PAD. The majority of individuals with PAD had at least one important cardiovascular risk factor advanced enough to be considered eligible for an aggressive treatment.

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Authors+Show Affiliations

Carbayo JA
Medical Corps, 14th Fighter Wing Air Base, Albacete, Spain.
Divisón JA
No affiliation info available
Escribano J
No affiliation info available
López-Abril J
No affiliation info available
López de Coca E
No affiliation info available
Artigao LM
No affiliation info available
Martínez E
No affiliation info available
Sanchis C
No affiliation info available
Massó J
No affiliation info available
Carrión L
No affiliation info available
Grupo de Enfermedades Vasculares de Albacete (GEVA)
No affiliation info available

MeSH

AdultAgedAnkleBlood PressureBrachial ArteryFemaleHumansMaleMiddle AgedPeripheral Vascular DiseasesPrevalenceRisk FactorsSex Characteristics

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17174225

Citation

Carbayo, Julio A., et al. "Using Ankle-brachial Index to Detect Peripheral Arterial Disease: Prevalence and Associated Risk Factors in a Random Population Sample." Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, vol. 17, no. 1, 2007, pp. 41-9.
Carbayo JA, Divisón JA, Escribano J, et al. Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample. Nutr Metab Cardiovasc Dis. 2007;17(1):41-9.
Carbayo, J. A., Divisón, J. A., Escribano, J., López-Abril, J., López de Coca, E., Artigao, L. M., Martínez, E., Sanchis, C., Massó, J., & Carrión, L. (2007). Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample. Nutrition, Metabolism, and Cardiovascular Diseases : NMCD, 17(1), 41-9.
Carbayo JA, et al. Using Ankle-brachial Index to Detect Peripheral Arterial Disease: Prevalence and Associated Risk Factors in a Random Population Sample. Nutr Metab Cardiovasc Dis. 2007;17(1):41-9. PubMed PMID: 17174225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using ankle-brachial index to detect peripheral arterial disease: prevalence and associated risk factors in a random population sample. AU - Carbayo,Julio A, AU - Divisón,Juan A, AU - Escribano,Julio, AU - López-Abril,Juan, AU - López de Coca,Enrique, AU - Artigao,Luis M, AU - Martínez,Esperanza, AU - Sanchis,Carlos, AU - Massó,Javier, AU - Carrión,Lucinio, AU - ,, Y1 - 2006/03/06/ PY - 2004/07/29/received PY - 2005/03/07/revised PY - 2005/08/05/accepted PY - 2006/12/19/pubmed PY - 2007/1/5/medline PY - 2006/12/19/entrez SP - 41 EP - 9 JF - Nutrition, metabolism, and cardiovascular diseases : NMCD JO - Nutr Metab Cardiovasc Dis VL - 17 IS - 1 N2 - BACKGROUND AND AIM: The ankle-brachial index (ABI) is being used increasingly to diagnose peripheral arterial disease (PAD) that predicts cardiovascular morbidity and mortality. The aim of this study is to determine the prevalence of PAD and associated risk factors in a Spanish random population sample of age > or =40. METHODS AND RESULTS: PAD is defined as an ABI<0.9 in either leg. 784 participants of age > or =40 were randomly selected in a Spanish province. 55.4% of them were female. The prevalence of PAD in this sample was 10.5% (95% confidence interval (CI) 8.4-12.8); 9.7% in females and 11.4% in males. In logistic regression analyses, adjusted for age and gender, smoking per 10 pack-years (odds ratio (OR) 1.40, 95% CI 1.23-1.58), hypertension (OR 1.85, 95% CI 1.05-3.28), hypercholesterolemia (OR 1.76, 95% CI 1.04-2.98), and diabetes (OR 1.80, 95% CI 1.04-3.11) were positively associated with prevalent PAD. More than 91% of persons with PAD had one or more cardiovascular disease risk factors. CONCLUSIONS: We conclude that in our study hypertension, hypercholesterolemia, diabetes mellitus and smoking are associated with PAD. The majority of individuals with PAD had at least one important cardiovascular risk factor advanced enough to be considered eligible for an aggressive treatment. SN - 1590-3729 UR - https://www.unboundmedicine.com/medline/citation/17174225/Using_ankle_brachial_index_to_detect_peripheral_arterial_disease:_prevalence_and_associated_risk_factors_in_a_random_population_sample_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0939-4753(05)00214-0 DB - PRIME DP - Unbound Medicine ER -