Tags

Type your tag names separated by a space and hit enter

Successful aortic valve replacement for Heyde syndrome with confirmed hematologic recovery.
Ann Thorac Surg 2007; 83(1):287-8AT

Abstract

Aortic valve stenosis can be complicated by recurrent gastrointestinal bleeding, particularly that due to angiodysplasia, also called Heyde syndrome. Recently, acquired type 2A von Willebrand disease, which is characterized by the loss of the large multimer of von Willebrand factor by the shear stress of aortic valve stenosis, was reported to be associated with this hemorrhagic syndrome. A 78-year-old woman, with severe aortic stenosis, presented with advanced anemia due to recurrent gastrointestinal bleeding and was diagnosed Heyde syndrome. By perioperative supplementation of von Willebrand factor and factor VIII, aortic valve replacement was safely performed without gastrointestinal bleeding. After the operation, the multimer of von Willebrand factor was normalized and thereafter no gastrointestinal bleeding occurred. This case reports the successful aortic valve replacement for Heyde syndrome, with confirmed hematologic recovery.

Authors+Show Affiliations

Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17184682

Citation

Morishima, Atsutomo, et al. "Successful Aortic Valve Replacement for Heyde Syndrome With Confirmed Hematologic Recovery." The Annals of Thoracic Surgery, vol. 83, no. 1, 2007, pp. 287-8.
Morishima A, Marui A, Shimamoto T, et al. Successful aortic valve replacement for Heyde syndrome with confirmed hematologic recovery. Ann Thorac Surg. 2007;83(1):287-8.
Morishima, A., Marui, A., Shimamoto, T., Saji, Y., Tambara, K., Nishina, T., & Komeda, M. (2007). Successful aortic valve replacement for Heyde syndrome with confirmed hematologic recovery. The Annals of Thoracic Surgery, 83(1), pp. 287-8.
Morishima A, et al. Successful Aortic Valve Replacement for Heyde Syndrome With Confirmed Hematologic Recovery. Ann Thorac Surg. 2007;83(1):287-8. PubMed PMID: 17184682.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Successful aortic valve replacement for Heyde syndrome with confirmed hematologic recovery. AU - Morishima,Atsutomo, AU - Marui,Akira, AU - Shimamoto,Takeshi, AU - Saji,Yoshiaki, AU - Tambara,Keiichi, AU - Nishina,Takeshi, AU - Komeda,Masashi, PY - 2006/03/08/received PY - 2006/04/28/revised PY - 2006/05/16/accepted PY - 2006/12/23/pubmed PY - 2007/1/5/medline PY - 2006/12/23/entrez SP - 287 EP - 8 JF - The Annals of thoracic surgery JO - Ann. Thorac. Surg. VL - 83 IS - 1 N2 - Aortic valve stenosis can be complicated by recurrent gastrointestinal bleeding, particularly that due to angiodysplasia, also called Heyde syndrome. Recently, acquired type 2A von Willebrand disease, which is characterized by the loss of the large multimer of von Willebrand factor by the shear stress of aortic valve stenosis, was reported to be associated with this hemorrhagic syndrome. A 78-year-old woman, with severe aortic stenosis, presented with advanced anemia due to recurrent gastrointestinal bleeding and was diagnosed Heyde syndrome. By perioperative supplementation of von Willebrand factor and factor VIII, aortic valve replacement was safely performed without gastrointestinal bleeding. After the operation, the multimer of von Willebrand factor was normalized and thereafter no gastrointestinal bleeding occurred. This case reports the successful aortic valve replacement for Heyde syndrome, with confirmed hematologic recovery. SN - 1552-6259 UR - https://www.unboundmedicine.com/medline/citation/17184682/Successful_aortic_valve_replacement_for_Heyde_syndrome_with_confirmed_hematologic_recovery_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-4975(06)01092-7 DB - PRIME DP - Unbound Medicine ER -