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Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia.
Jpn J Infect Dis. 2006 Dec; 59(6):388-90.JJ

Abstract

The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumoniae antigen test. The urinary antigen test was positive in 9 (15.3%) of 59 patients enrolled in the study and in 8 (73%) of 11 patients with pneumococcal pneumonia confirmed by conventional methods. The test revealed a sensitivity of 72.7% and a specificity of 97.6% with conventional microbiological criteria used as the reference standard. The positive predictive value was 88.9% and the negative predictive value was 93%. We concluded that the urinary antigen test can supplement conventional microbiological tests in the diagnosis of pneumococcal pneumonia.

Authors+Show Affiliations

Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. sercis@hacettepe.edu.trNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17186959

Citation

Ercis, Serpil, et al. "Validation of Urinary Antigen Test for Streptococcus Pneumoniae in Patients With Pneumococcal Pneumonia." Japanese Journal of Infectious Diseases, vol. 59, no. 6, 2006, pp. 388-90.
Ercis S, Ergin A, Sahin GO, et al. Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia. Jpn J Infect Dis. 2006;59(6):388-90.
Ercis, S., Ergin, A., Sahin, G. O., Hasçelik, G., & Uzun, O. (2006). Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia. Japanese Journal of Infectious Diseases, 59(6), 388-90.
Ercis S, et al. Validation of Urinary Antigen Test for Streptococcus Pneumoniae in Patients With Pneumococcal Pneumonia. Jpn J Infect Dis. 2006;59(6):388-90. PubMed PMID: 17186959.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Validation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia. AU - Ercis,Serpil, AU - Ergin,Alper, AU - Sahin,Gülşen Ozkaya, AU - Hasçelik,Gülşen, AU - Uzun,Omrüm, PY - 2006/12/26/pubmed PY - 2007/4/26/medline PY - 2006/12/26/entrez SP - 388 EP - 90 JF - Japanese journal of infectious diseases JO - Jpn J Infect Dis VL - 59 IS - 6 N2 - The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumoniae antigen test. The urinary antigen test was positive in 9 (15.3%) of 59 patients enrolled in the study and in 8 (73%) of 11 patients with pneumococcal pneumonia confirmed by conventional methods. The test revealed a sensitivity of 72.7% and a specificity of 97.6% with conventional microbiological criteria used as the reference standard. The positive predictive value was 88.9% and the negative predictive value was 93%. We concluded that the urinary antigen test can supplement conventional microbiological tests in the diagnosis of pneumococcal pneumonia. SN - 1344-6304 UR - https://www.unboundmedicine.com/medline/citation/17186959/Validation_of_urinary_antigen_test_for_Streptococcus_pneumoniae_in_patients_with_pneumococcal_pneumonia_ DB - PRIME DP - Unbound Medicine ER -