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Distribution of anemia associated with micronutrient deficiencies other than iron in a probabilistic sample of Mexican children.
Ann Nutr Metab. 2006; 50(6):506-11.AN

Abstract

BACKGROUND

This investigation aims to explore the association among anemia and vitamins A, C, and folate deficiencies in a probabilistic sample of Mexican children.

METHODS

Data on hemoglobin, serum vitamins A and C and folate concentrations and percent transferrin saturation (PTS) in children 0.5-11 years (n = 1,770) were extracted from the database of the probabilistic Mexican National Nutrition Survey 1999 (NNS-99).

RESULTS

Overall, 16.6% of children were anemic. Iron deficiency children with or without anemia had more frequent low serum retinol (40.6 vs. 16% and 27.7 vs. 11.9%, p < 0.05, respectively) and lower hemoglobin folate (11.5 vs. 22%, p < 0.05) than their non-iron deficiency counterparts. Mean concentrations of serum iron (p < 0.01), folate (p < 0.001) and retinol (p < 0.0001), but not ascorbic acid (p < 0.6), were significantly lower in anemic than in nonanemic children. In a linear regression model, 15% of hemoglobin variation in children was explained by retinol, folate and PTS, but not vitamin C (p <0.0001).

CONCLUSION

Anemia was mostly associated with iron deficiency and with a lesser proportion of folate and vitamin A deficiencies. Vitamin A deficiency might be overestimated since iron deficiency may lower serum retinol concentrations. Interventions aimed to reduce anemia in this population must consider interactions between those micronutrients in designing strategies.

Authors+Show Affiliations

Center for Research on Nutrition and Health, Instituto Nacional de Salud Pública, Cuernavaca, Mexico. svillalp@insp.mxNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17191024

Citation

Villalpando, Salvador, et al. "Distribution of Anemia Associated With Micronutrient Deficiencies Other Than Iron in a Probabilistic Sample of Mexican Children." Annals of Nutrition & Metabolism, vol. 50, no. 6, 2006, pp. 506-11.
Villalpando S, Pérez-Expósito AB, Shamah-Levy T, et al. Distribution of anemia associated with micronutrient deficiencies other than iron in a probabilistic sample of Mexican children. Ann Nutr Metab. 2006;50(6):506-11.
Villalpando, S., Pérez-Expósito, A. B., Shamah-Levy, T., & Rivera, J. A. (2006). Distribution of anemia associated with micronutrient deficiencies other than iron in a probabilistic sample of Mexican children. Annals of Nutrition & Metabolism, 50(6), 506-11.
Villalpando S, et al. Distribution of Anemia Associated With Micronutrient Deficiencies Other Than Iron in a Probabilistic Sample of Mexican Children. Ann Nutr Metab. 2006;50(6):506-11. PubMed PMID: 17191024.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Distribution of anemia associated with micronutrient deficiencies other than iron in a probabilistic sample of Mexican children. AU - Villalpando,Salvador, AU - Pérez-Expósito,Ana Beatriz, AU - Shamah-Levy,Teresa, AU - Rivera,Juan A, Y1 - 2006/12/21/ PY - 2005/07/06/received PY - 2006/07/27/accepted PY - 2006/12/28/pubmed PY - 2007/2/24/medline PY - 2006/12/28/entrez SP - 506 EP - 11 JF - Annals of nutrition & metabolism JO - Ann. Nutr. Metab. VL - 50 IS - 6 N2 - BACKGROUND: This investigation aims to explore the association among anemia and vitamins A, C, and folate deficiencies in a probabilistic sample of Mexican children. METHODS: Data on hemoglobin, serum vitamins A and C and folate concentrations and percent transferrin saturation (PTS) in children 0.5-11 years (n = 1,770) were extracted from the database of the probabilistic Mexican National Nutrition Survey 1999 (NNS-99). RESULTS: Overall, 16.6% of children were anemic. Iron deficiency children with or without anemia had more frequent low serum retinol (40.6 vs. 16% and 27.7 vs. 11.9%, p < 0.05, respectively) and lower hemoglobin folate (11.5 vs. 22%, p < 0.05) than their non-iron deficiency counterparts. Mean concentrations of serum iron (p < 0.01), folate (p < 0.001) and retinol (p < 0.0001), but not ascorbic acid (p < 0.6), were significantly lower in anemic than in nonanemic children. In a linear regression model, 15% of hemoglobin variation in children was explained by retinol, folate and PTS, but not vitamin C (p <0.0001). CONCLUSION: Anemia was mostly associated with iron deficiency and with a lesser proportion of folate and vitamin A deficiencies. Vitamin A deficiency might be overestimated since iron deficiency may lower serum retinol concentrations. Interventions aimed to reduce anemia in this population must consider interactions between those micronutrients in designing strategies. SN - 1421-9697 UR - https://www.unboundmedicine.com/medline/citation/17191024/Distribution_of_anemia_associated_with_micronutrient_deficiencies_other_than_iron_in_a_probabilistic_sample_of_Mexican_children_ L2 - https://www.karger.com?DOI=10.1159/000098142 DB - PRIME DP - Unbound Medicine ER -