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Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp.
Dermatology. 2007; 214(1):21-4.D

Abstract

BACKGROUND

Videocapillaroscopy (VCP) can be used to explore microcirculatory modifications in skin diseases. Psoriasis shows specific capillary alterations reflecting typical histopathological changes.

OBJECTIVE

To compare capillary morphology, distribution and density in psoriasis and seborrheic dermatitis of the scalp for differential diagnosis.

METHODS

VCP was performed on histology-confirmed scalp lesions of 30 patients with chronic plaque psoriasis, 30 age- and sex-matched patients with seborrheic dermatitis and 30 healthy subjects. The morphology, mean density per mm(2) and mean diameter of capillary loops was measured.

RESULTS

Scalp psoriasis exhibited homogeneously tortuous and dilated capillaries (bushy pattern), with a 73 +/- 17 mum (mean +/- standard deviation) diameter of capillary bushes. In contrast, scalp seborrheic dermatitis presented a multiform pattern, with mildly tortuous capillary loops and isolated dilated capillaries, but a substantial preservation of local microangioarchitecture. Mean diameter of capillary bush was significantly lower (27 +/- 4 microm; p < 0.001) and similar to that of the scalp of healthy subjects (21 +/- 5 microm). Capillary loop density was similar in patients with psoriasis (23 +/- 5/mm(2)) seborrheic dermatitis (24 +/- 2/mm(2)) and healthy scalp skin (24 +/- 3/mm(2)).

CONCLUSION

VCP could be a useful noninvasive approach for differentiating between psoriasis and seborrheic dermatitis, especially when the scalp is the only affected site.

Authors+Show Affiliations

Section of Dermatology and Venereology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy. paolo.rosina@univr.itNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17191043

Citation

Rosina, Paolo, et al. "Videocapillaroscopy in the Differential Diagnosis Between Psoriasis and Seborrheic Dermatitis of the Scalp." Dermatology (Basel, Switzerland), vol. 214, no. 1, 2007, pp. 21-4.
Rosina P, Zamperetti MR, Giovannini A, et al. Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp. Dermatology. 2007;214(1):21-4.
Rosina, P., Zamperetti, M. R., Giovannini, A., & Girolomoni, G. (2007). Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp. Dermatology (Basel, Switzerland), 214(1), 21-4.
Rosina P, et al. Videocapillaroscopy in the Differential Diagnosis Between Psoriasis and Seborrheic Dermatitis of the Scalp. Dermatology. 2007;214(1):21-4. PubMed PMID: 17191043.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp. AU - Rosina,Paolo, AU - Zamperetti,Maria Rosa, AU - Giovannini,Andrea, AU - Girolomoni,Giampiero, PY - 2006/05/17/received PY - 2006/07/04/accepted PY - 2006/12/28/pubmed PY - 2007/2/21/medline PY - 2006/12/28/entrez SP - 21 EP - 4 JF - Dermatology (Basel, Switzerland) JO - Dermatology VL - 214 IS - 1 N2 - BACKGROUND: Videocapillaroscopy (VCP) can be used to explore microcirculatory modifications in skin diseases. Psoriasis shows specific capillary alterations reflecting typical histopathological changes. OBJECTIVE: To compare capillary morphology, distribution and density in psoriasis and seborrheic dermatitis of the scalp for differential diagnosis. METHODS: VCP was performed on histology-confirmed scalp lesions of 30 patients with chronic plaque psoriasis, 30 age- and sex-matched patients with seborrheic dermatitis and 30 healthy subjects. The morphology, mean density per mm(2) and mean diameter of capillary loops was measured. RESULTS: Scalp psoriasis exhibited homogeneously tortuous and dilated capillaries (bushy pattern), with a 73 +/- 17 mum (mean +/- standard deviation) diameter of capillary bushes. In contrast, scalp seborrheic dermatitis presented a multiform pattern, with mildly tortuous capillary loops and isolated dilated capillaries, but a substantial preservation of local microangioarchitecture. Mean diameter of capillary bush was significantly lower (27 +/- 4 microm; p < 0.001) and similar to that of the scalp of healthy subjects (21 +/- 5 microm). Capillary loop density was similar in patients with psoriasis (23 +/- 5/mm(2)) seborrheic dermatitis (24 +/- 2/mm(2)) and healthy scalp skin (24 +/- 3/mm(2)). CONCLUSION: VCP could be a useful noninvasive approach for differentiating between psoriasis and seborrheic dermatitis, especially when the scalp is the only affected site. SN - 1018-8665 UR - https://www.unboundmedicine.com/medline/citation/17191043/Videocapillaroscopy_in_the_differential_diagnosis_between_psoriasis_and_seborrheic_dermatitis_of_the_scalp_ DB - PRIME DP - Unbound Medicine ER -