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Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions.
Org Lett. 2007 Jan 04; 9(1):57-60.OL

Abstract

[reaction: see text] A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel-Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented.

Authors+Show Affiliations

Basavaiah D
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. dbsc@uohyd.ernet.in
Reddy KR
No affiliation info available

MeSH

Crystallography, X-RayEthylenesHydrogenIndenesIndolesModels, MolecularMolecular StructureOxindolesSpiro Compounds

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17192084

Citation

Basavaiah, Deevi, and Kanumuri Ramesh Reddy. "Simple and One-pot Protocol for Synthesis of Indene-spiro-oxindoles Involving Tandem Prins and Friedel-Crafts Reactions." Organic Letters, vol. 9, no. 1, 2007, pp. 57-60.
Basavaiah D, Reddy KR. Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions. Org Lett. 2007;9(1):57-60.
Basavaiah, D., & Reddy, K. R. (2007). Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions. Organic Letters, 9(1), 57-60.
Basavaiah D, Reddy KR. Simple and One-pot Protocol for Synthesis of Indene-spiro-oxindoles Involving Tandem Prins and Friedel-Crafts Reactions. Org Lett. 2007 Jan 4;9(1):57-60. PubMed PMID: 17192084.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions. AU - Basavaiah,Deevi, AU - Reddy,Kanumuri Ramesh, PY - 2006/12/29/pubmed PY - 2007/2/21/medline PY - 2006/12/29/entrez SP - 57 EP - 60 JF - Organic letters JO - Org Lett VL - 9 IS - 1 N2 - [reaction: see text] A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel-Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/17192084/Simple_and_one_pot_protocol_for_synthesis_of_indene_spiro_oxindoles_involving_tandem_Prins_and_Friedel_Crafts_reactions_ L2 - https://doi.org/10.1021/ol062561m DB - PRIME DP - Unbound Medicine ER -