Synthesis of indenes by the transition metal-mediated carboannulation of alkynes.J Org Chem. 2007 Jan 05; 72(1):251-62.JO
Abstract
The synthesis of highly substituted indenes has been achieved by three different transition metal-mediated methods. The first method involves the palladium-catalyzed carboannulation of internal alkynes. The second method utilizes a two-step approach, which involves first the palladium/copper-catalyzed cross-coupling of terminal alkynes with appropriately functionalized aryl halides, followed by copper-catalyzed intramolecular cyclization. The third method involves intermolecular palladium-catalyzed arylation of the arylalkynes formed in the first step of the second method.
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Language
eng
PubMed ID
17194107
Citation
Zhang, Daohua, et al. "Synthesis of Indenes By the Transition Metal-mediated Carboannulation of Alkynes." The Journal of Organic Chemistry, vol. 72, no. 1, 2007, pp. 251-62.
Zhang D, Liu Z, Yum EK, et al. Synthesis of indenes by the transition metal-mediated carboannulation of alkynes. J Org Chem. 2007;72(1):251-62.
Zhang, D., Liu, Z., Yum, E. K., & Larock, R. C. (2007). Synthesis of indenes by the transition metal-mediated carboannulation of alkynes. The Journal of Organic Chemistry, 72(1), 251-62.
Zhang D, et al. Synthesis of Indenes By the Transition Metal-mediated Carboannulation of Alkynes. J Org Chem. 2007 Jan 5;72(1):251-62. PubMed PMID: 17194107.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Synthesis of indenes by the transition metal-mediated carboannulation of alkynes.
AU - Zhang,Daohua,
AU - Liu,Zhijian,
AU - Yum,Eul K,
AU - Larock,Richard C,
PY - 2006/12/30/pubmed
PY - 2007/2/14/medline
PY - 2006/12/30/entrez
SP - 251
EP - 62
JF - The Journal of organic chemistry
JO - J Org Chem
VL - 72
IS - 1
N2 - The synthesis of highly substituted indenes has been achieved by three different transition metal-mediated methods. The first method involves the palladium-catalyzed carboannulation of internal alkynes. The second method utilizes a two-step approach, which involves first the palladium/copper-catalyzed cross-coupling of terminal alkynes with appropriately functionalized aryl halides, followed by copper-catalyzed intramolecular cyclization. The third method involves intermolecular palladium-catalyzed arylation of the arylalkynes formed in the first step of the second method.
SN - 0022-3263
UR - https://www.unboundmedicine.com/medline/citation/17194107/Synthesis_of_indenes_by_the_transition_metal_mediated_carboannulation_of_alkynes_
L2 - https://doi.org/10.1021/jo0620563
DB - PRIME
DP - Unbound Medicine
ER -
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