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Lifetime prevalence of psychotic and bipolar I disorders in a general population.
Arch Gen Psychiatry. 2007 Jan; 64(1):19-28.AG

Abstract

CONTEXT

Recent general population surveys of psychotic disorders have found low lifetime prevalences. However, this may be owing to methodological problems. Few studies have reported the prevalences of all specific psychotic disorders.

OBJECTIVE

To provide reliable estimates of the lifetime prevalences of specific psychotic disorders.

DESIGN

General population survey.

SETTING AND PARTICIPANTS

A nationally representative sample of 8028 persons 30 years or older was screened for psychotic and bipolar I disorders using the Composite International Diagnostic Interview, self-reported diagnoses, medical examination, and national registers. Those selected by the screens were then re-interviewed with the Structured Clinical Interview for DSM-IV. Best-estimate DSM-IV diagnoses were formed by combining the interview and case note data. Register diagnoses were used to estimate the effect of the nonresponders.

MAIN OUTCOME MEASURES

Diagnosis of any psychotic or bipolar I disorder according to the DSM-IV criteria.

RESULTS

The lifetime prevalence of all psychotic disorders was 3.06% and rose to 3.48% when register diagnoses of the nonresponder group were included. Lifetime prevalences were as follows: 0.87% for schizophrenia, 0.32% for schizoaffective disorder, 0.07% for schizophreniform disorder, 0.18% for delusional disorder, 0.24% for bipolar I disorder, 0.35% for major depressive disorder with psychotic features, 0.42% for substance-induced psychotic disorders, and 0.21% for psychotic disorders due to a general medical condition. The National Hospital Discharge Register was the most reliable of the screens (kappa = 0.80). Case notes supplementing the interviews were essential for specific diagnoses of psychotic disorders.

CONCLUSIONS

Multiple sources of information are essential for accurate estimation of lifetime prevalences of psychotic disorders. The use of comprehensive methods reveals that their lifetime prevalence exceeds 3%.

Authors+Show Affiliations

Department of Mental Health and Alcohol Research, National Public Health Institute, University of Helsinki, Mannerheimintie 166, 0300 Helsinki, Finland. jonna.perala@ktl.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17199051

Citation

Perälä, Jonna, et al. "Lifetime Prevalence of Psychotic and Bipolar I Disorders in a General Population." Archives of General Psychiatry, vol. 64, no. 1, 2007, pp. 19-28.
Perälä J, Suvisaari J, Saarni SI, et al. Lifetime prevalence of psychotic and bipolar I disorders in a general population. Arch Gen Psychiatry. 2007;64(1):19-28.
Perälä, J., Suvisaari, J., Saarni, S. I., Kuoppasalmi, K., Isometsä, E., Pirkola, S., Partonen, T., Tuulio-Henriksson, A., Hintikka, J., Kieseppä, T., Härkänen, T., Koskinen, S., & Lönnqvist, J. (2007). Lifetime prevalence of psychotic and bipolar I disorders in a general population. Archives of General Psychiatry, 64(1), 19-28.
Perälä J, et al. Lifetime Prevalence of Psychotic and Bipolar I Disorders in a General Population. Arch Gen Psychiatry. 2007;64(1):19-28. PubMed PMID: 17199051.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lifetime prevalence of psychotic and bipolar I disorders in a general population. AU - Perälä,Jonna, AU - Suvisaari,Jaana, AU - Saarni,Samuli I, AU - Kuoppasalmi,Kimmo, AU - Isometsä,Erkki, AU - Pirkola,Sami, AU - Partonen,Timo, AU - Tuulio-Henriksson,Annamari, AU - Hintikka,Jukka, AU - Kieseppä,Tuula, AU - Härkänen,Tommi, AU - Koskinen,Seppo, AU - Lönnqvist,Jouko, PY - 2007/1/3/pubmed PY - 2007/3/1/medline PY - 2007/1/3/entrez SP - 19 EP - 28 JF - Archives of general psychiatry JO - Arch Gen Psychiatry VL - 64 IS - 1 N2 - CONTEXT: Recent general population surveys of psychotic disorders have found low lifetime prevalences. However, this may be owing to methodological problems. Few studies have reported the prevalences of all specific psychotic disorders. OBJECTIVE: To provide reliable estimates of the lifetime prevalences of specific psychotic disorders. DESIGN: General population survey. SETTING AND PARTICIPANTS: A nationally representative sample of 8028 persons 30 years or older was screened for psychotic and bipolar I disorders using the Composite International Diagnostic Interview, self-reported diagnoses, medical examination, and national registers. Those selected by the screens were then re-interviewed with the Structured Clinical Interview for DSM-IV. Best-estimate DSM-IV diagnoses were formed by combining the interview and case note data. Register diagnoses were used to estimate the effect of the nonresponders. MAIN OUTCOME MEASURES: Diagnosis of any psychotic or bipolar I disorder according to the DSM-IV criteria. RESULTS: The lifetime prevalence of all psychotic disorders was 3.06% and rose to 3.48% when register diagnoses of the nonresponder group were included. Lifetime prevalences were as follows: 0.87% for schizophrenia, 0.32% for schizoaffective disorder, 0.07% for schizophreniform disorder, 0.18% for delusional disorder, 0.24% for bipolar I disorder, 0.35% for major depressive disorder with psychotic features, 0.42% for substance-induced psychotic disorders, and 0.21% for psychotic disorders due to a general medical condition. The National Hospital Discharge Register was the most reliable of the screens (kappa = 0.80). Case notes supplementing the interviews were essential for specific diagnoses of psychotic disorders. CONCLUSIONS: Multiple sources of information are essential for accurate estimation of lifetime prevalences of psychotic disorders. The use of comprehensive methods reveals that their lifetime prevalence exceeds 3%. SN - 0003-990X UR - https://www.unboundmedicine.com/medline/citation/17199051/Lifetime_prevalence_of_psychotic_and_bipolar_I_disorders_in_a_general_population_ L2 - https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/archpsyc.64.1.19 DB - PRIME DP - Unbound Medicine ER -