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[Twelve-month outcome of 658 patients with acute coronary syndrome without ST-segment elevation assigned to early invasive strategy].
Wiad Lek 2006; 59(7-8):497-501WL

Abstract

We aimed at assessing the frequency of death, myocardial infarction, unstable angina, repeat revascularization, cardiovascular hospitalisation during 12 months in patients assigned to early invasive strategy.

MATERIAL AND METHOD

We analysed 658 consecutive patients with acute coronary syndrome (ACS) without ST-segment elevation hospitalized between January 2000 and February 2003. Patients had to fulfill the following criteria: 1) rest angina within 24 hours prior to admission, 2) at least one of the following: ST-segment depression (> or = 0,05 mV), transient (< 20 min) ST-segment elevation (> or = 0,05 mV), T-wave inversion (> or = 1 mV) in at least 2 contiguous leads, positive serum cardiac markers.

RESULTS

All patients underwent coronary angiography followed by PCI (percutaneous coronary interventions) in 71.8% of patients. 18.2% were assigned to CABG (coronary artery bypass graft) and 8.7% of patients were treated conservatively. 1.3% of patients underwent PCI followed by an elective CABG surgery. In-hospital mortality rate was.,3%. 3.3% patients died after hospital discharge. The frequency of myocardial infarction, unstable angina and repeat PCI at 12 months was 2.1%, 16.8% and 11.5% respectively. The rate of cardiovascular hospitalisation was 15.6%. Multivariate analysis identified two independent predictors ofdeath: diabetes mellitus (OR: 7.02, 95% CI: 1.5-13.8, p = 0.03) and heart failure (OR: 12.6, 95% CI: 2.86-16.6 p = 0.005).

CONCLUSIONS

Early invasive strategy in analysed group yields good long-term outcomes with low rate of adverse ischemic events. Independent predictors of deaths were diabetes mellitus and heart failure.

Authors+Show Affiliations

Z III Katedry i Oddzialu Klinicznego Kardiologii Slaskiej Akademii Medycznej, Katowicach Slaskie Centrum Chorób Serca, Zabrzu. b.szygula@sccs.plNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

pol

PubMed ID

17209347

Citation

Szyguła-Jurkiewicz, Bozena, et al. "[Twelve-month Outcome of 658 Patients With Acute Coronary Syndrome Without ST-segment Elevation Assigned to Early Invasive Strategy]." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 59, no. 7-8, 2006, pp. 497-501.
Szyguła-Jurkiewicz B, Wasilewski J, Wilczek K, et al. [Twelve-month outcome of 658 patients with acute coronary syndrome without ST-segment elevation assigned to early invasive strategy]. Wiad Lek. 2006;59(7-8):497-501.
Szyguła-Jurkiewicz, B., Wasilewski, J., Wilczek, K., Osadnik, T., Trzeciak, P., Lekston, A., ... Poloński, L. (2006). [Twelve-month outcome of 658 patients with acute coronary syndrome without ST-segment elevation assigned to early invasive strategy]. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 59(7-8), pp. 497-501.
Szyguła-Jurkiewicz B, et al. [Twelve-month Outcome of 658 Patients With Acute Coronary Syndrome Without ST-segment Elevation Assigned to Early Invasive Strategy]. Wiad Lek. 2006;59(7-8):497-501. PubMed PMID: 17209347.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Twelve-month outcome of 658 patients with acute coronary syndrome without ST-segment elevation assigned to early invasive strategy]. AU - Szyguła-Jurkiewicz,Bozena, AU - Wasilewski,Jarosław, AU - Wilczek,Krzysztof, AU - Osadnik,Tadeusz, AU - Trzeciak,Przemysław, AU - Lekston,Andrzej, AU - Wojnicz,Romuald, AU - Poloński,Lech, PY - 2007/1/11/pubmed PY - 2007/4/27/medline PY - 2007/1/11/entrez SP - 497 EP - 501 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad. Lek. VL - 59 IS - 7-8 N2 - UNLABELLED: We aimed at assessing the frequency of death, myocardial infarction, unstable angina, repeat revascularization, cardiovascular hospitalisation during 12 months in patients assigned to early invasive strategy. MATERIAL AND METHOD: We analysed 658 consecutive patients with acute coronary syndrome (ACS) without ST-segment elevation hospitalized between January 2000 and February 2003. Patients had to fulfill the following criteria: 1) rest angina within 24 hours prior to admission, 2) at least one of the following: ST-segment depression (> or = 0,05 mV), transient (< 20 min) ST-segment elevation (> or = 0,05 mV), T-wave inversion (> or = 1 mV) in at least 2 contiguous leads, positive serum cardiac markers. RESULTS: All patients underwent coronary angiography followed by PCI (percutaneous coronary interventions) in 71.8% of patients. 18.2% were assigned to CABG (coronary artery bypass graft) and 8.7% of patients were treated conservatively. 1.3% of patients underwent PCI followed by an elective CABG surgery. In-hospital mortality rate was.,3%. 3.3% patients died after hospital discharge. The frequency of myocardial infarction, unstable angina and repeat PCI at 12 months was 2.1%, 16.8% and 11.5% respectively. The rate of cardiovascular hospitalisation was 15.6%. Multivariate analysis identified two independent predictors ofdeath: diabetes mellitus (OR: 7.02, 95% CI: 1.5-13.8, p = 0.03) and heart failure (OR: 12.6, 95% CI: 2.86-16.6 p = 0.005). CONCLUSIONS: Early invasive strategy in analysed group yields good long-term outcomes with low rate of adverse ischemic events. Independent predictors of deaths were diabetes mellitus and heart failure. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/17209347/[Twelve_month_outcome_of_658_patients_with_acute_coronary_syndrome_without_ST_segment_elevation_assigned_to_early_invasive_strategy]_ L2 - https://medlineplus.gov/coronaryarterybypasssurgery.html DB - PRIME DP - Unbound Medicine ER -