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Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income.
Artif Organs. 2007 Jan; 31(1):53-60.AO

Abstract

The importance of measuring health-related quality of life (HRQoL) in patients on maintenance hemodialysis (HD) is being increasingly recognized, but few studies, especially from the Balkan region, have addressed this issue. The aims of this study were (i) to evaluate HRQoL in an outpatient university-affiliated dialysis facility in South Serbia; (ii) to determine the effects of age, presence of comorbidity, primary kidney disease, dose of HD, and family income; and (iii) to make comparisons of the HRQoL in Serbian patients on chronic HD with that reported by others previously. The study enrolled 192 patients on HD for more than 3 months. Comorbidity was assessed using the index of coexistent diseases (ICED), including two subindexes: index of disease severity (IDS) and index of physical impairment (IPI). Patient's self-assessment of HRQoL was measured by the 36-item short form health survey questionnaire (SF-36), encompassing eight summary scales and two summary dimensions. Ten of the baseline variables had significant associations with parameters of HRQoL. Fitting these variables in linear regression models resulted in 41.9% variance for physical dimension of HRQoL (physical component summary score [PCS]), and 32.5% for mental dimension of HRQoL (mental component summary score [MCS]). However, statistically significant effect had only IDS, IPI, and age for PCS, and income of patients for MCS. We found that an increase in IDS score for one unit is associated with a decrease of PCS by 13.2%, and SF-36 score (total quality of life) by 15.2%. The increase of IPI score by one unit decreases PCS by 16.1% and SF-36 score by 17.5%. A 5-year increase in age is associated with a decrease of PCS by 3.1%, and SF-36 score by 3.8%. The monthly income increase of 10 euros per family member increases MCS by 5.2% and SF-36 score by 3.0%. HRQoL in patients on HD was found markedly impaired. Comorbid conditions have negative and statistically significant correlation with parameters of HRQoL, and could explain poor HRQoL to a remarkable extent. Older age and poor income substantially reduce HRQoL in HD patients.

Authors+Show Affiliations

Institute of Nephrology and Hemodialysis, Faculty of Medicine, Nis, Serbia.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17209961

Citation

Stojanovic, Miomir, and Vladisav Stefanovic. "Assessment of Health-related Quality of Life in Patients Treated With Hemodialysis in Serbia: Influence of Comorbidity, Age, and Income." Artificial Organs, vol. 31, no. 1, 2007, pp. 53-60.
Stojanovic M, Stefanovic V. Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income. Artif Organs. 2007;31(1):53-60.
Stojanovic, M., & Stefanovic, V. (2007). Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income. Artificial Organs, 31(1), 53-60.
Stojanovic M, Stefanovic V. Assessment of Health-related Quality of Life in Patients Treated With Hemodialysis in Serbia: Influence of Comorbidity, Age, and Income. Artif Organs. 2007;31(1):53-60. PubMed PMID: 17209961.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income. AU - Stojanovic,Miomir, AU - Stefanovic,Vladisav, PY - 2007/1/11/pubmed PY - 2007/3/23/medline PY - 2007/1/11/entrez SP - 53 EP - 60 JF - Artificial organs JO - Artif Organs VL - 31 IS - 1 N2 - The importance of measuring health-related quality of life (HRQoL) in patients on maintenance hemodialysis (HD) is being increasingly recognized, but few studies, especially from the Balkan region, have addressed this issue. The aims of this study were (i) to evaluate HRQoL in an outpatient university-affiliated dialysis facility in South Serbia; (ii) to determine the effects of age, presence of comorbidity, primary kidney disease, dose of HD, and family income; and (iii) to make comparisons of the HRQoL in Serbian patients on chronic HD with that reported by others previously. The study enrolled 192 patients on HD for more than 3 months. Comorbidity was assessed using the index of coexistent diseases (ICED), including two subindexes: index of disease severity (IDS) and index of physical impairment (IPI). Patient's self-assessment of HRQoL was measured by the 36-item short form health survey questionnaire (SF-36), encompassing eight summary scales and two summary dimensions. Ten of the baseline variables had significant associations with parameters of HRQoL. Fitting these variables in linear regression models resulted in 41.9% variance for physical dimension of HRQoL (physical component summary score [PCS]), and 32.5% for mental dimension of HRQoL (mental component summary score [MCS]). However, statistically significant effect had only IDS, IPI, and age for PCS, and income of patients for MCS. We found that an increase in IDS score for one unit is associated with a decrease of PCS by 13.2%, and SF-36 score (total quality of life) by 15.2%. The increase of IPI score by one unit decreases PCS by 16.1% and SF-36 score by 17.5%. A 5-year increase in age is associated with a decrease of PCS by 3.1%, and SF-36 score by 3.8%. The monthly income increase of 10 euros per family member increases MCS by 5.2% and SF-36 score by 3.0%. HRQoL in patients on HD was found markedly impaired. Comorbid conditions have negative and statistically significant correlation with parameters of HRQoL, and could explain poor HRQoL to a remarkable extent. Older age and poor income substantially reduce HRQoL in HD patients. SN - 0160-564X UR - https://www.unboundmedicine.com/medline/citation/17209961/Assessment_of_health_related_quality_of_life_in_patients_treated_with_hemodialysis_in_Serbia:_influence_of_comorbidity_age_and_income_ L2 - https://doi.org/10.1111/j.1525-1594.2007.00340.x DB - PRIME DP - Unbound Medicine ER -