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Correlation of anemia, secondary hyperparathyroidism with left ventricular hypertrophy in Chronic Kidney Disease patients.
J Assoc Physicians India. 2006 Sep; 54:699-703.JA

Abstract

AIMS

To demonstrate the correlation of anemia and intact parathormone with left ventricular hypertrophy in a cohort of Chronic Kidney Disease (CKD) patients in a tertiary care centre.

METHODS

A cross-sectional study was done over 2 years on 230 renal failure patients (160 males, 70 females), aged 15-75 years, who had elevated serum creatinine and reduced GFR. The patients were assessed based on clinical history and a number of laboratory parameters including serum creatinine, calcium, iPTH level, Hb, Hct, GFR and LVMI. Settings : Patients were seen as inpatients and outpatients in a tertiary care centre.

RESULTS

In CKD stages I, II and III, 51% of the patients had anemia Hb<11gm/dl), 16%of the patients had elevated iPTH, 79% of male patients and 71% of female patients had LVH. In Stage IV CKD, 55% of the patients had anemia, 25% of the patients had elevated iPTH, 74% of male patients and 100% of female patients had LVH. In stage V CKD, 76% of the patients had anemia, 31% of the patients had elevated iPTH, 77% of male patients and 96% of female patients had LVH. In all five stages, 78% of male patients and 71% of female patients with elevated iPTH had LVH, 81% of male patients and 90% of female patients with anemia had LVH. Systemic hypertension was present in 69% of the patients.

CONCLUSION

Anemia is widely prevalent in our cohort of CKD patients. Severity of anemia is correlated to LVH and secondary hyperparathyroidism in these patients.

Authors+Show Affiliations

Department of Medicine, Madras Medical Mission, Chennai.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17212016

Citation

Datta, Sanchari, et al. "Correlation of Anemia, Secondary Hyperparathyroidism With Left Ventricular Hypertrophy in Chronic Kidney Disease Patients." The Journal of the Association of Physicians of India, vol. 54, 2006, pp. 699-703.
Datta S, Abraham G, Mathew M, et al. Correlation of anemia, secondary hyperparathyroidism with left ventricular hypertrophy in Chronic Kidney Disease patients. J Assoc Physicians India. 2006;54:699-703.
Datta, S., Abraham, G., Mathew, M., Somasundaram, H., Muralidharan, T. R., Moorthy, A., Sathyasekaran, ., & Leslie, N. (2006). Correlation of anemia, secondary hyperparathyroidism with left ventricular hypertrophy in Chronic Kidney Disease patients. The Journal of the Association of Physicians of India, 54, 699-703.
Datta S, et al. Correlation of Anemia, Secondary Hyperparathyroidism With Left Ventricular Hypertrophy in Chronic Kidney Disease Patients. J Assoc Physicians India. 2006;54:699-703. PubMed PMID: 17212016.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation of anemia, secondary hyperparathyroidism with left ventricular hypertrophy in Chronic Kidney Disease patients. AU - Datta,Sanchari, AU - Abraham,G, AU - Mathew,Milly, AU - Somasundaram,H, AU - Muralidharan,T R, AU - Moorthy,Asha, AU - Sathyasekaran,, AU - Leslie,Nancy, PY - 2007/1/11/pubmed PY - 2007/2/17/medline PY - 2007/1/11/entrez SP - 699 EP - 703 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 54 N2 - AIMS: To demonstrate the correlation of anemia and intact parathormone with left ventricular hypertrophy in a cohort of Chronic Kidney Disease (CKD) patients in a tertiary care centre. METHODS: A cross-sectional study was done over 2 years on 230 renal failure patients (160 males, 70 females), aged 15-75 years, who had elevated serum creatinine and reduced GFR. The patients were assessed based on clinical history and a number of laboratory parameters including serum creatinine, calcium, iPTH level, Hb, Hct, GFR and LVMI. Settings : Patients were seen as inpatients and outpatients in a tertiary care centre. RESULTS: In CKD stages I, II and III, 51% of the patients had anemia Hb<11gm/dl), 16%of the patients had elevated iPTH, 79% of male patients and 71% of female patients had LVH. In Stage IV CKD, 55% of the patients had anemia, 25% of the patients had elevated iPTH, 74% of male patients and 100% of female patients had LVH. In stage V CKD, 76% of the patients had anemia, 31% of the patients had elevated iPTH, 77% of male patients and 96% of female patients had LVH. In all five stages, 78% of male patients and 71% of female patients with elevated iPTH had LVH, 81% of male patients and 90% of female patients with anemia had LVH. Systemic hypertension was present in 69% of the patients. CONCLUSION: Anemia is widely prevalent in our cohort of CKD patients. Severity of anemia is correlated to LVH and secondary hyperparathyroidism in these patients. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/17212016/Correlation_of_anemia_secondary_hyperparathyroidism_with_left_ventricular_hypertrophy_in_Chronic_Kidney_Disease_patients_ L2 - http://www.diseaseinfosearch.org/result/3996 DB - PRIME DP - Unbound Medicine ER -