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Platinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles.
Org Lett. 2007 Jan 18; 9(2):367-70.OL

Abstract

Cyclic enesulfonamides, enecarbamates, or enamides tethered to an alkyne cyclize readily with use of platinum(II) chloride. This reaction generates quaternary-substituted carbon centers within simple spiro-fused or more complex tri- and tetracyclic heterocyclic ring systems. The yields for this process range from 50% to 83%. [reaction: see text].

Authors+Show Affiliations

Harrison TJ
Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z1.
Patrick BO
No affiliation info available
Dake GR
No affiliation info available

MeSH

AlkenesAlkynesAmidesCarbamatesCarbonCatalysisCyclizationMolecular StructurePlatinum CompoundsStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17217306

Citation

Harrison, Tyler J., et al. "Platinum(II)-catalyzed Cyclizations Forming Quaternary Carbon Centers, Using Enesulfonamides, Enecarbamates, or Enamides as Nucleophiles." Organic Letters, vol. 9, no. 2, 2007, pp. 367-70.
Harrison TJ, Patrick BO, Dake GR. Platinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles. Org Lett. 2007;9(2):367-70.
Harrison, T. J., Patrick, B. O., & Dake, G. R. (2007). Platinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles. Organic Letters, 9(2), 367-70.
Harrison TJ, Patrick BO, Dake GR. Platinum(II)-catalyzed Cyclizations Forming Quaternary Carbon Centers, Using Enesulfonamides, Enecarbamates, or Enamides as Nucleophiles. Org Lett. 2007 Jan 18;9(2):367-70. PubMed PMID: 17217306.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Platinum(II)-catalyzed cyclizations forming quaternary carbon centers, using enesulfonamides, enecarbamates, or enamides as nucleophiles. AU - Harrison,Tyler J, AU - Patrick,Brian O, AU - Dake,Gregory R, PY - 2007/1/16/pubmed PY - 2007/3/21/medline PY - 2007/1/16/entrez SP - 367 EP - 70 JF - Organic letters JO - Org Lett VL - 9 IS - 2 N2 - Cyclic enesulfonamides, enecarbamates, or enamides tethered to an alkyne cyclize readily with use of platinum(II) chloride. This reaction generates quaternary-substituted carbon centers within simple spiro-fused or more complex tri- and tetracyclic heterocyclic ring systems. The yields for this process range from 50% to 83%. [reaction: see text]. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/17217306/Platinum_II__catalyzed_cyclizations_forming_quaternary_carbon_centers_using_enesulfonamides_enecarbamates_or_enamides_as_nucleophiles_ L2 - https://doi.org/10.1021/ol062939g DB - PRIME DP - Unbound Medicine ER -