Tags

Type your tag names separated by a space and hit enter

Change over time of bowel habit in irritable bowel syndrome: a prospective, observational, 1-year follow-up study (RITMO study).
Aliment Pharmacol Ther. 2007 Feb 01; 25(3):323-32.AP

Abstract

BACKGROUND

Evolution of bowel habit in irritable bowel syndrome (IBS) is not well known.

AIM

To evaluate the change over time of bowel habit in IBS patients followed-up during 1 year.

METHODS

Five hundred and seventeen patients with IBS were prospectively included in an observational study with five evaluations over a 1-year period. Symptoms were recorded daily in diary cards during four 4-week periods along the study. Bristol Stool Scale (BSS) was used to define bowel habit.

RESULTS

Four-hundred patients completed the study. Rome II showed low-moderate agreement (42%) with BSS to define bowel habit. Frequency of constipation and diarrhoea showed little changes throughout the study. Over 50% of the patients had the same bowel habit when each diary was compared with the next one. A third of patients maintained the same habit throughout the study. Most changes occurred from/to mixed or unsubtyped IBS. Only 14% of cases changed from constipation to diarrhoea or vice versa. This change was associated to female gender (OR: 2.65).

CONCLUSIONS

The frequency of constipation and diarrhoea remains relatively stable over time. Changes in IBS subtypes are common, but changes between constipation and diarrhoea are rare. Alternating IBS is more frequent in women.

Authors+Show Affiliations

Digestive Medicine Department, Hospital Universitari La Fe, Valencia, Spain. garrigues_vic@gva.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17217445

Citation

Garrigues, V, et al. "Change Over Time of Bowel Habit in Irritable Bowel Syndrome: a Prospective, Observational, 1-year Follow-up Study (RITMO Study)." Alimentary Pharmacology & Therapeutics, vol. 25, no. 3, 2007, pp. 323-32.
Garrigues V, Mearin F, Badía X, et al. Change over time of bowel habit in irritable bowel syndrome: a prospective, observational, 1-year follow-up study (RITMO study). Aliment Pharmacol Ther. 2007;25(3):323-32.
Garrigues, V., Mearin, F., Badía, X., Balboa, A., Benavent, J., Caballero, A., Domínguez, E., Díaz-Rubio, M., Roset, M., Figueras, M., & Cucala, M. (2007). Change over time of bowel habit in irritable bowel syndrome: a prospective, observational, 1-year follow-up study (RITMO study). Alimentary Pharmacology & Therapeutics, 25(3), 323-32.
Garrigues V, et al. Change Over Time of Bowel Habit in Irritable Bowel Syndrome: a Prospective, Observational, 1-year Follow-up Study (RITMO Study). Aliment Pharmacol Ther. 2007 Feb 1;25(3):323-32. PubMed PMID: 17217445.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Change over time of bowel habit in irritable bowel syndrome: a prospective, observational, 1-year follow-up study (RITMO study). AU - Garrigues,V, AU - Mearin,F, AU - Badía,X, AU - Balboa,A, AU - Benavent,J, AU - Caballero,A, AU - Domínguez,E, AU - Díaz-Rubio,M, AU - Roset,M, AU - Figueras,M, AU - Cucala,M, AU - ,, Y1 - 2007/01/08/ PY - 2007/1/16/pubmed PY - 2007/5/22/medline PY - 2007/1/16/entrez SP - 323 EP - 32 JF - Alimentary pharmacology & therapeutics JO - Aliment Pharmacol Ther VL - 25 IS - 3 N2 - BACKGROUND: Evolution of bowel habit in irritable bowel syndrome (IBS) is not well known. AIM: To evaluate the change over time of bowel habit in IBS patients followed-up during 1 year. METHODS: Five hundred and seventeen patients with IBS were prospectively included in an observational study with five evaluations over a 1-year period. Symptoms were recorded daily in diary cards during four 4-week periods along the study. Bristol Stool Scale (BSS) was used to define bowel habit. RESULTS: Four-hundred patients completed the study. Rome II showed low-moderate agreement (42%) with BSS to define bowel habit. Frequency of constipation and diarrhoea showed little changes throughout the study. Over 50% of the patients had the same bowel habit when each diary was compared with the next one. A third of patients maintained the same habit throughout the study. Most changes occurred from/to mixed or unsubtyped IBS. Only 14% of cases changed from constipation to diarrhoea or vice versa. This change was associated to female gender (OR: 2.65). CONCLUSIONS: The frequency of constipation and diarrhoea remains relatively stable over time. Changes in IBS subtypes are common, but changes between constipation and diarrhoea are rare. Alternating IBS is more frequent in women. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/17217445/Change_over_time_of_bowel_habit_in_irritable_bowel_syndrome:_a_prospective_observational_1_year_follow_up_study__RITMO_study__ L2 - https://doi.org/10.1111/j.1365-2036.2006.03197.x DB - PRIME DP - Unbound Medicine ER -