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A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies.
Australas J Dermatol. 2007 Feb; 48(1):46-9.AJ

Abstract

An 83-year-old Caucasian woman presented with a 25-year history of an itchy, eczematous blistering eruption affecting her trunk and acral sites. She had a past history of adenocarcinoma of the lung, colorectal carcinoma and bladder carcinoma. Several skin biopsies consistently showed features of a spongiotic process. Direct and indirect immunofluorescence studies were repeatedly negative, excluding the possibility of an autoimmune blistering disorder. A skin biopsy several years later, however, showed histological and immunophenotypic features of mycosis fungoides. The literature on this rare phenotype of cutaneous T-cell lymphoma generally portrays a negative prognosis. Our case illustrates an excellent prognosis with stable disease 30 years after onset.

Authors+Show Affiliations

Royal Adelaide Hospital, Department of Dermatology, Adelaide, SA, Australia. annette.pearce@ozemail.com.auNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17222304

Citation

Pearce, Annette, et al. "A 30-year History of CD4+ Vesiculo-bullous Mycosis Fungoides and Multiple Visceral Malignancies." The Australasian Journal of Dermatology, vol. 48, no. 1, 2007, pp. 46-9.
Pearce A, Reid C, Gramp A, et al. A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies. Australas J Dermatol. 2007;48(1):46-9.
Pearce, A., Reid, C., Gramp, A., & Sidhu, S. (2007). A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies. The Australasian Journal of Dermatology, 48(1), 46-9.
Pearce A, et al. A 30-year History of CD4+ Vesiculo-bullous Mycosis Fungoides and Multiple Visceral Malignancies. Australas J Dermatol. 2007;48(1):46-9. PubMed PMID: 17222304.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies. AU - Pearce,Annette, AU - Reid,Catherine, AU - Gramp,Amanda, AU - Sidhu,Shireen, PY - 2007/1/16/pubmed PY - 2007/3/10/medline PY - 2007/1/16/entrez SP - 46 EP - 9 JF - The Australasian journal of dermatology JO - Australas J Dermatol VL - 48 IS - 1 N2 - An 83-year-old Caucasian woman presented with a 25-year history of an itchy, eczematous blistering eruption affecting her trunk and acral sites. She had a past history of adenocarcinoma of the lung, colorectal carcinoma and bladder carcinoma. Several skin biopsies consistently showed features of a spongiotic process. Direct and indirect immunofluorescence studies were repeatedly negative, excluding the possibility of an autoimmune blistering disorder. A skin biopsy several years later, however, showed histological and immunophenotypic features of mycosis fungoides. The literature on this rare phenotype of cutaneous T-cell lymphoma generally portrays a negative prognosis. Our case illustrates an excellent prognosis with stable disease 30 years after onset. SN - 0004-8380 UR - https://www.unboundmedicine.com/medline/citation/17222304/A_30_year_history_of_CD4+_vesiculo_bullous_mycosis_fungoides_and_multiple_visceral_malignancies_ L2 - https://doi.org/10.1111/j.1440-0960.2007.00333.x DB - PRIME DP - Unbound Medicine ER -