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Is the metabolic syndrome an independent risk factor for erectile dysfunction?
J Urol 2007; 177(2):651-4JU

Abstract

PURPOSE

We determined the role of the metabolic syndrome as an independent risk factor for erectile dysfunction.

MATERIALS AND METHODS

Men participating in a health screening project completed the International Index of Erectile Function-5. The metabolic syndrome was defined according to the 2005 International Diabetes Federation consensus definition. Multiple linear regression, ANOVA and chi-square tests were used to investigate the impact of the metabolic syndrome on erectile dysfunction.

RESULTS

A total of 2,371 men with a mean age of 46.1 years (SD 9.9, range 30 to 69) were analyzed. Of the men 33.4% (652) had no erectile dysfunction (International Index of Erectile Function-5 score 22 to 25), 59.7% (1,166) had mild erectile dysfunction (International Index of Erectile Function-5 score 17 to 21) and 6.9% (134) had moderate to severe erectile dysfunction (International Index of Erectile Function-5 score 5 to 16). The metabolic syndrome was present in 33.8% (794). In a multiple linear regression analysis an increased waist-to-hip ratio (p = 0.01) and metabolic syndrome (p = 0.01) turned out to be independently associated with a decreased International Index of Erectile Function-5 score. When stratified according to age, the metabolic syndrome was correlated to erectile dysfunction only in men 50 years old or older with an increase of severe erectile dysfunction by 48% (p = 0.01).

CONCLUSIONS

The metabolic syndrome and an increased waist-to-hip ratio are independently associated with a decreased International Index of Erectile Function-5 score. The metabolic syndrome in men older than 50 years is significantly associated with a higher proportion of moderate to severe erectile dysfunction.

Authors+Show Affiliations

Department of Urology and Andrology, Donauspital, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17222651

Citation

Heidler, Stefan, et al. "Is the Metabolic Syndrome an Independent Risk Factor for Erectile Dysfunction?" The Journal of Urology, vol. 177, no. 2, 2007, pp. 651-4.
Heidler S, Temml C, Broessner C, et al. Is the metabolic syndrome an independent risk factor for erectile dysfunction? J Urol. 2007;177(2):651-4.
Heidler, S., Temml, C., Broessner, C., Mock, K., Rauchenwald, M., Madersbacher, S., & Ponholzer, A. (2007). Is the metabolic syndrome an independent risk factor for erectile dysfunction? The Journal of Urology, 177(2), pp. 651-4.
Heidler S, et al. Is the Metabolic Syndrome an Independent Risk Factor for Erectile Dysfunction. J Urol. 2007;177(2):651-4. PubMed PMID: 17222651.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is the metabolic syndrome an independent risk factor for erectile dysfunction? AU - Heidler,Stefan, AU - Temml,Christian, AU - Broessner,Clemens, AU - Mock,Karl, AU - Rauchenwald,Michael, AU - Madersbacher,Stephan, AU - Ponholzer,Anton, PY - 2006/03/16/received PY - 2007/1/16/pubmed PY - 2007/2/28/medline PY - 2007/1/16/entrez SP - 651 EP - 4 JF - The Journal of urology JO - J. Urol. VL - 177 IS - 2 N2 - PURPOSE: We determined the role of the metabolic syndrome as an independent risk factor for erectile dysfunction. MATERIALS AND METHODS: Men participating in a health screening project completed the International Index of Erectile Function-5. The metabolic syndrome was defined according to the 2005 International Diabetes Federation consensus definition. Multiple linear regression, ANOVA and chi-square tests were used to investigate the impact of the metabolic syndrome on erectile dysfunction. RESULTS: A total of 2,371 men with a mean age of 46.1 years (SD 9.9, range 30 to 69) were analyzed. Of the men 33.4% (652) had no erectile dysfunction (International Index of Erectile Function-5 score 22 to 25), 59.7% (1,166) had mild erectile dysfunction (International Index of Erectile Function-5 score 17 to 21) and 6.9% (134) had moderate to severe erectile dysfunction (International Index of Erectile Function-5 score 5 to 16). The metabolic syndrome was present in 33.8% (794). In a multiple linear regression analysis an increased waist-to-hip ratio (p = 0.01) and metabolic syndrome (p = 0.01) turned out to be independently associated with a decreased International Index of Erectile Function-5 score. When stratified according to age, the metabolic syndrome was correlated to erectile dysfunction only in men 50 years old or older with an increase of severe erectile dysfunction by 48% (p = 0.01). CONCLUSIONS: The metabolic syndrome and an increased waist-to-hip ratio are independently associated with a decreased International Index of Erectile Function-5 score. The metabolic syndrome in men older than 50 years is significantly associated with a higher proportion of moderate to severe erectile dysfunction. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/17222651/Is_the_metabolic_syndrome_an_independent_risk_factor_for_erectile_dysfunction L2 - https://www.jurology.com/doi/full/10.1016/j.juro.2006.09.043?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -