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[Simultaneous determination of three active constituents in cortex moutan by RP-HPLC].
Zhongguo Zhong Yao Za Zhi. 2006 Oct; 31(20):1699-701.ZZ

Abstract

OBJECTIVE

To establish a RP-HPLC method for the simultaneous determination of gallic acid, paeoniflorin and paeonol in Cortex Moutan.

METHOD

The analysis was carried out on a column of YMC-C18 (4. 6 mm x 250 mm, 5 microm), and gradient elution was used for the baseline separation of these three constituents with the different detection wavelength.

RESULT

The linear ranges for gallic acid, paeoniflorin and paeonol were 0.0130-0.267, 0.0880-1.76 and 0.164-3.28 microg, respectively. Their average recoveries were 104.3%, 101.7% and 99.5%, respectively.

CONCLUSION

The method was successfully applied to the determination of gallic acid, paeoniflorin and paeonol in Cortex Moutan from the different drugstores. It was shown in this study that the proposed method could be used to evaluate the quality of the medicinal plants or herbal preparations containing gallic acid, paeoniflorin and paeonol.

Authors+Show Affiliations

Wang YW
Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
Yu K
No affiliation info available
Cheng YY
No affiliation info available

MeSH

AcetophenonesBenzoatesBridged-Ring CompoundsChromatography, High Pressure LiquidDrugs, Chinese HerbalGallic AcidGlucosidesMonoterpenesPaeoniaPlant BarkPlants, MedicinalQuality ControlReproducibility of Results

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

17225540

Citation

Wang, Yu-Wen, et al. "[Simultaneous Determination of Three Active Constituents in Cortex Moutan By RP-HPLC]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 31, no. 20, 2006, pp. 1699-701.
Wang YW, Yu K, Cheng YY. [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC]. Zhongguo Zhong Yao Za Zhi. 2006;31(20):1699-701.
Wang, Y. W., Yu, K., & Cheng, Y. Y. (2006). [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 31(20), 1699-701.
Wang YW, Yu K, Cheng YY. [Simultaneous Determination of Three Active Constituents in Cortex Moutan By RP-HPLC]. Zhongguo Zhong Yao Za Zhi. 2006;31(20):1699-701. PubMed PMID: 17225540.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC]. AU - Wang,Yu-Wen, AU - Yu,Ke, AU - Cheng,Yi-Yu, PY - 2007/1/18/pubmed PY - 2007/12/6/medline PY - 2007/1/18/entrez SP - 1699 EP - 701 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 31 IS - 20 N2 - OBJECTIVE: To establish a RP-HPLC method for the simultaneous determination of gallic acid, paeoniflorin and paeonol in Cortex Moutan. METHOD: The analysis was carried out on a column of YMC-C18 (4. 6 mm x 250 mm, 5 microm), and gradient elution was used for the baseline separation of these three constituents with the different detection wavelength. RESULT: The linear ranges for gallic acid, paeoniflorin and paeonol were 0.0130-0.267, 0.0880-1.76 and 0.164-3.28 microg, respectively. Their average recoveries were 104.3%, 101.7% and 99.5%, respectively. CONCLUSION: The method was successfully applied to the determination of gallic acid, paeoniflorin and paeonol in Cortex Moutan from the different drugstores. It was shown in this study that the proposed method could be used to evaluate the quality of the medicinal plants or herbal preparations containing gallic acid, paeoniflorin and paeonol. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/17225540/[Simultaneous_determination_of_three_active_constituents_in_cortex_moutan_by_RP_HPLC]_ DB - PRIME DP - Unbound Medicine ER -