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Apolipoprotein E epsilon4 allele is associated with Parkinson disease risk in a Mexican Mestizo population.
Mov Disord. 2007 Feb 15; 22(3):417-20.MD

Abstract

We investigated the association between apolipoprotein E (APOE) alleles and genotypes and Parkinson disease (PD) in 229 unrelated Mexican Mestizo PD patients and 229 controls. Results showed that both APOE-epsilon4 allele and APOE epsilon4/epsilon3 genotype are associated with PD (OR = 1.736, P = 0.011; OR = 1.688, P = 0.019, respectively). Mean age at onset of PD was not associated to any APOE allele or genotype, but was significantly earlier in familial PD when compared to sporadic cases (P = 0.025).

Authors+Show Affiliations

Department of Biological Systems, Universidad Autónoma Metropolitana Xochimilco, Mexico City, Mexico.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17230455

Citation

López, Marisol, et al. "Apolipoprotein E Epsilon4 Allele Is Associated With Parkinson Disease Risk in a Mexican Mestizo Population." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 22, no. 3, 2007, pp. 417-20.
López M, Guerrero J, Yescas P, et al. Apolipoprotein E epsilon4 allele is associated with Parkinson disease risk in a Mexican Mestizo population. Mov Disord. 2007;22(3):417-20.
López, M., Guerrero, J., Yescas, P., Boll, M. C., Familiar, I., Ochoa, A., Rasmussen, A., & Alonso, M. E. (2007). Apolipoprotein E epsilon4 allele is associated with Parkinson disease risk in a Mexican Mestizo population. Movement Disorders : Official Journal of the Movement Disorder Society, 22(3), 417-20.
López M, et al. Apolipoprotein E Epsilon4 Allele Is Associated With Parkinson Disease Risk in a Mexican Mestizo Population. Mov Disord. 2007 Feb 15;22(3):417-20. PubMed PMID: 17230455.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Apolipoprotein E epsilon4 allele is associated with Parkinson disease risk in a Mexican Mestizo population. AU - López,Marisol, AU - Guerrero,Jorge, AU - Yescas,Petra, AU - Boll,Marie-Catherine, AU - Familiar,Itziar, AU - Ochoa,Adriana, AU - Rasmussen,Astrid, AU - Alonso,María Elisa, PY - 2007/1/19/pubmed PY - 2007/5/2/medline PY - 2007/1/19/entrez SP - 417 EP - 20 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 22 IS - 3 N2 - We investigated the association between apolipoprotein E (APOE) alleles and genotypes and Parkinson disease (PD) in 229 unrelated Mexican Mestizo PD patients and 229 controls. Results showed that both APOE-epsilon4 allele and APOE epsilon4/epsilon3 genotype are associated with PD (OR = 1.736, P = 0.011; OR = 1.688, P = 0.019, respectively). Mean age at onset of PD was not associated to any APOE allele or genotype, but was significantly earlier in familial PD when compared to sporadic cases (P = 0.025). SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/17230455/Apolipoprotein_E_epsilon4_allele_is_associated_with_Parkinson_disease_risk_in_a_Mexican_Mestizo_population_ L2 - https://doi.org/10.1002/mds.21340 DB - PRIME DP - Unbound Medicine ER -