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Neurologic disease associated with 17D-204 yellow fever vaccination: a report of 15 cases.
Vaccine. 2007 Feb 26; 25(10):1727-34.V

Abstract

Yellow fever (YF), can be prevented by an attenuated vaccine (YEL). We reviewed neurologic adverse events (AE) following YEL that were reported to the national Vaccine Adverse Events Reporting System (VAERS). VAERS is a passive reporting system with inherent limitations for causality assessment. Based on defined criteria, five cases of encephalitis were classified as 'definitely' and one of acute disseminated encephalomyelitis (ADEM) as 'probably' caused by YEL. Six cases of Guillain-Barre Syndrome (GBS), one of encephalitis, and two of ADEM, were classified as 'suspect' vaccine-associated disease. Laboratory and epidemiological evidence suggests that YEL caused encephalitis. Additional studies will be required to confirm whether YEL can rarely result in GBS and/or ADEM.

Authors+Show Affiliations

1401 Rockville Pike, HFM-220, Rockville, MD 20852, USA. ann.mcmahon@fda.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17240001

Citation

McMahon, Ann W., et al. "Neurologic Disease Associated With 17D-204 Yellow Fever Vaccination: a Report of 15 Cases." Vaccine, vol. 25, no. 10, 2007, pp. 1727-34.
McMahon AW, Eidex RB, Marfin AA, et al. Neurologic disease associated with 17D-204 yellow fever vaccination: a report of 15 cases. Vaccine. 2007;25(10):1727-34.
McMahon, A. W., Eidex, R. B., Marfin, A. A., Russell, M., Sejvar, J. J., Markoff, L., Hayes, E. B., Chen, R. T., Ball, R., Braun, M. M., & Cetron, M. (2007). Neurologic disease associated with 17D-204 yellow fever vaccination: a report of 15 cases. Vaccine, 25(10), 1727-34.
McMahon AW, et al. Neurologic Disease Associated With 17D-204 Yellow Fever Vaccination: a Report of 15 Cases. Vaccine. 2007 Feb 26;25(10):1727-34. PubMed PMID: 17240001.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurologic disease associated with 17D-204 yellow fever vaccination: a report of 15 cases. AU - McMahon,Ann W, AU - Eidex,Rachel B, AU - Marfin,Anthony A, AU - Russell,Michelle, AU - Sejvar,James J, AU - Markoff,Lewis, AU - Hayes,Edward B, AU - Chen,Robert T, AU - Ball,Robert, AU - Braun,M Miles, AU - Cetron,Martin, AU - ,, Y1 - 2006/11/27/ PY - 2006/08/18/received PY - 2006/11/07/revised PY - 2006/11/13/accepted PY - 2007/1/24/pubmed PY - 2007/8/19/medline PY - 2007/1/24/entrez SP - 1727 EP - 34 JF - Vaccine JO - Vaccine VL - 25 IS - 10 N2 - Yellow fever (YF), can be prevented by an attenuated vaccine (YEL). We reviewed neurologic adverse events (AE) following YEL that were reported to the national Vaccine Adverse Events Reporting System (VAERS). VAERS is a passive reporting system with inherent limitations for causality assessment. Based on defined criteria, five cases of encephalitis were classified as 'definitely' and one of acute disseminated encephalomyelitis (ADEM) as 'probably' caused by YEL. Six cases of Guillain-Barre Syndrome (GBS), one of encephalitis, and two of ADEM, were classified as 'suspect' vaccine-associated disease. Laboratory and epidemiological evidence suggests that YEL caused encephalitis. Additional studies will be required to confirm whether YEL can rarely result in GBS and/or ADEM. SN - 0264-410X UR - https://www.unboundmedicine.com/medline/citation/17240001/Neurologic_disease_associated_with_17D_204_yellow_fever_vaccination:_a_report_of_15_cases_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(06)01229-1 DB - PRIME DP - Unbound Medicine ER -