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A clinical investigation of the efficacy of three different treatment regimens for the control of plaque and gingivitis.
J Clin Dent. 2006; 17(5):138-44.JC

Abstract

OBJECTIVE

The objective of this examiner-blind clinical study was to investigate the efficacy of three oral hygiene regimens for the control of gingivitis and supragingival plaque.

METHODOLOGY

Following a baseline examination for gingivitis and supragingival plaque, qualifying adult male and female subjects from the San Francisco, California area were stratified into three treatment groups, which were balanced for plaque. The groups were then randomly assigned to one of three oral hygiene regimens: 1) twice-daily tooth brushing with Colgate Total Toothpaste, accompanied by once-daily flossing after brushing; 2) twice-daily tooth brushing with Colgate Total Toothpaste without flossing; and 3) twice-daily tooth brushing with a sodium fluoride toothpaste, accompanied by once-daily flossing after brushing. All subjects were given a complete oral prophylaxis, and dispensed their assigned treatment product(s), along with a soft-bristled adult toothbrush for home use. All dentifrice products were supplied in the original packaging to which overwrapping had been applied. Subjects were instructed to brush their teeth for one minute twice daily (morning and evening) using only the dentifrice provided, and to refrain from using anything other than their assigned oral hygiene products for the duration of the study. In addition, subjects were instructed to refrain from any routine dental treatment (except emergency) during the course of the study. There were no restrictions regarding diet or smoking habits over the course of the study. Examinations for gingivitis and supragingival plaque, and oral soft tissue assessments were repeated after three months, and again after six months of product use.

RESULTS

One-hundred fourteen (114) subjects complied with the protocol and completed the six-month examinations. Statistical analyses showed similar results for both whole-mouth and interproximal scoring sites after six months of product use. Although not statistically significant, subjects using Colgate Total Toothpaste accompanied by the use of dental floss had numerically lower six-month scores for gingivitis and supragingival plaque formation when compared to the scores of subjects using Colgate Total Toothpaste without the use of dental floss. Relative to the sodium fluoride toothpaste accompanied by the use of dental floss, subjects using Colgate Total Toothpaste, both with and without the use of dental floss, exhibited statistically significant reductions in gingivitis and supragingival plaque formation after six months of product use.

CONCLUSION

The results of this clinical study support the conclusion that the use of Colgate Total Toothpaste, both with and without the use of dental floss, provided statistically significant improvements over the sodium fluoride toothpaste plus flossing regimen with respect to the control of gingivitis and supragingival plaque formation. Although not statistically significant, numerically lower six-month scores for gingivitis and supragingival plaque were associated with Colgate Total Toothpaste accompanied by the use of dental floss, when compared with Colgate Total Toothpaste without the use of dental floss.

Authors+Show Affiliations

School of Dentistry, University of the Pacific, San Francisco, CA, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17240933

Citation

Schiff, Thomas, et al. "A Clinical Investigation of the Efficacy of Three Different Treatment Regimens for the Control of Plaque and Gingivitis." The Journal of Clinical Dentistry, vol. 17, no. 5, 2006, pp. 138-44.
Schiff T, Proskin HM, Zhang YP, et al. A clinical investigation of the efficacy of three different treatment regimens for the control of plaque and gingivitis. J Clin Dent. 2006;17(5):138-44.
Schiff, T., Proskin, H. M., Zhang, Y. P., Petrone, M., & DeVizio, W. (2006). A clinical investigation of the efficacy of three different treatment regimens for the control of plaque and gingivitis. The Journal of Clinical Dentistry, 17(5), 138-44.
Schiff T, et al. A Clinical Investigation of the Efficacy of Three Different Treatment Regimens for the Control of Plaque and Gingivitis. J Clin Dent. 2006;17(5):138-44. PubMed PMID: 17240933.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A clinical investigation of the efficacy of three different treatment regimens for the control of plaque and gingivitis. AU - Schiff,Thomas, AU - Proskin,Howard M, AU - Zhang,Yun Po, AU - Petrone,Margaret, AU - DeVizio,William, PY - 2007/1/24/pubmed PY - 2007/6/15/medline PY - 2007/1/24/entrez SP - 138 EP - 44 JF - The Journal of clinical dentistry JO - J Clin Dent VL - 17 IS - 5 N2 - OBJECTIVE: The objective of this examiner-blind clinical study was to investigate the efficacy of three oral hygiene regimens for the control of gingivitis and supragingival plaque. METHODOLOGY: Following a baseline examination for gingivitis and supragingival plaque, qualifying adult male and female subjects from the San Francisco, California area were stratified into three treatment groups, which were balanced for plaque. The groups were then randomly assigned to one of three oral hygiene regimens: 1) twice-daily tooth brushing with Colgate Total Toothpaste, accompanied by once-daily flossing after brushing; 2) twice-daily tooth brushing with Colgate Total Toothpaste without flossing; and 3) twice-daily tooth brushing with a sodium fluoride toothpaste, accompanied by once-daily flossing after brushing. All subjects were given a complete oral prophylaxis, and dispensed their assigned treatment product(s), along with a soft-bristled adult toothbrush for home use. All dentifrice products were supplied in the original packaging to which overwrapping had been applied. Subjects were instructed to brush their teeth for one minute twice daily (morning and evening) using only the dentifrice provided, and to refrain from using anything other than their assigned oral hygiene products for the duration of the study. In addition, subjects were instructed to refrain from any routine dental treatment (except emergency) during the course of the study. There were no restrictions regarding diet or smoking habits over the course of the study. Examinations for gingivitis and supragingival plaque, and oral soft tissue assessments were repeated after three months, and again after six months of product use. RESULTS: One-hundred fourteen (114) subjects complied with the protocol and completed the six-month examinations. Statistical analyses showed similar results for both whole-mouth and interproximal scoring sites after six months of product use. Although not statistically significant, subjects using Colgate Total Toothpaste accompanied by the use of dental floss had numerically lower six-month scores for gingivitis and supragingival plaque formation when compared to the scores of subjects using Colgate Total Toothpaste without the use of dental floss. Relative to the sodium fluoride toothpaste accompanied by the use of dental floss, subjects using Colgate Total Toothpaste, both with and without the use of dental floss, exhibited statistically significant reductions in gingivitis and supragingival plaque formation after six months of product use. CONCLUSION: The results of this clinical study support the conclusion that the use of Colgate Total Toothpaste, both with and without the use of dental floss, provided statistically significant improvements over the sodium fluoride toothpaste plus flossing regimen with respect to the control of gingivitis and supragingival plaque formation. Although not statistically significant, numerically lower six-month scores for gingivitis and supragingival plaque were associated with Colgate Total Toothpaste accompanied by the use of dental floss, when compared with Colgate Total Toothpaste without the use of dental floss. SN - 0895-8831 UR - https://www.unboundmedicine.com/medline/citation/17240933/A_clinical_investigation_of_the_efficacy_of_three_different_treatment_regimens_for_the_control_of_plaque_and_gingivitis_ DB - PRIME DP - Unbound Medicine ER -