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Lip impressions: a new method for monitoring morphological changes in orofacial granulomatosis.
Oral Dis 2007; 13(1):93-8OD

Abstract

AIM

To develop and evaluate an objective method for assessing lip size and treatment-related morphological changes in orofacial granulomatosis (OFG) patients.

MATERIALS AND METHODS

Patients with swollen lips because of OFG (n=21) were enrolled. A light-body polyvinylsiloxane material was used to take lip impressions before and after treatment (n=10), or during treatment (n=11). Plaster models were cast from the impressions and the lips were measured using callipers. The intra-examiner and inter-examiner reproducibility of the technique were assessed.

RESULTS

OFG patients had significantly larger lips than controls (P<0.0001). The coefficient of variation on repeated measurements of the same impression was 1.6% and for duplicate impressions was 2.6%. Significant reduction in lip size was shown in all 10 patients after diet restriction (P<0.002). Seven of 11 patients whose impressions were taken at least 3 months after the initiation of cinnamon- and benzoate-free diet also showed reduction in lip size during follow up (P<0.002).

CONCLUSIONS

Serial lip impressions appear to be reliable for routine quantification of morphological changes of the lips in OFG patients. We present a new reproducible and sensitive method for assessing changes in lip size in response to treatment in OFG.

Authors+Show Affiliations

Department of Oral Medicine, King's College London Dental Institute of Guy's, King's College & St Thomas' Hospitals, London, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17241437

Citation

Chiandussi, S, et al. "Lip Impressions: a New Method for Monitoring Morphological Changes in Orofacial Granulomatosis." Oral Diseases, vol. 13, no. 1, 2007, pp. 93-8.
Chiandussi S, Tappuni AR, Watson TF, et al. Lip impressions: a new method for monitoring morphological changes in orofacial granulomatosis. Oral Dis. 2007;13(1):93-8.
Chiandussi, S., Tappuni, A. R., Watson, T. F., White, A., Escudier, M. P., Sanderson, J. D., & Challacombe, S. J. (2007). Lip impressions: a new method for monitoring morphological changes in orofacial granulomatosis. Oral Diseases, 13(1), pp. 93-8.
Chiandussi S, et al. Lip Impressions: a New Method for Monitoring Morphological Changes in Orofacial Granulomatosis. Oral Dis. 2007;13(1):93-8. PubMed PMID: 17241437.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lip impressions: a new method for monitoring morphological changes in orofacial granulomatosis. AU - Chiandussi,S, AU - Tappuni,A R, AU - Watson,T F, AU - White,A, AU - Escudier,M P, AU - Sanderson,J D, AU - Challacombe,S J, PY - 2007/1/24/pubmed PY - 2007/3/23/medline PY - 2007/1/24/entrez SP - 93 EP - 8 JF - Oral diseases JO - Oral Dis VL - 13 IS - 1 N2 - AIM: To develop and evaluate an objective method for assessing lip size and treatment-related morphological changes in orofacial granulomatosis (OFG) patients. MATERIALS AND METHODS: Patients with swollen lips because of OFG (n=21) were enrolled. A light-body polyvinylsiloxane material was used to take lip impressions before and after treatment (n=10), or during treatment (n=11). Plaster models were cast from the impressions and the lips were measured using callipers. The intra-examiner and inter-examiner reproducibility of the technique were assessed. RESULTS: OFG patients had significantly larger lips than controls (P<0.0001). The coefficient of variation on repeated measurements of the same impression was 1.6% and for duplicate impressions was 2.6%. Significant reduction in lip size was shown in all 10 patients after diet restriction (P<0.002). Seven of 11 patients whose impressions were taken at least 3 months after the initiation of cinnamon- and benzoate-free diet also showed reduction in lip size during follow up (P<0.002). CONCLUSIONS: Serial lip impressions appear to be reliable for routine quantification of morphological changes of the lips in OFG patients. We present a new reproducible and sensitive method for assessing changes in lip size in response to treatment in OFG. SN - 1354-523X UR - https://www.unboundmedicine.com/medline/citation/17241437/Lip_impressions:_a_new_method_for_monitoring_morphological_changes_in_orofacial_granulomatosis_ L2 - https://doi.org/10.1111/j.1601-0825.2006.01255.x DB - PRIME DP - Unbound Medicine ER -